ArticleHeredity2016
A method for detecting recent changes in contemporary effective population size from linkage disequilibrium at linked and unlinked loci.
Article in Heredity, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Combining Multiple Genetic Estimates of NMolecular ecology resources · 2026Article
- Genetic Surveillance Reveals Differential Evolutionary Dynamic of Anopheles gambiae Under Contrasting Insecticidal Tools Used in Malaria Control.Molecular ecology · 2026Article
- Effective Population Size Estimation in Large Marine Populations: Considering Current Challenges and Opportunities When Simulating Large Data Sets With High-Density Genomic Information.Evolutionary applications · 2025Review
- Levels and Spatial Patterns of Effective Population Sizes in the Southern Damselfly (Evolutionary applications · 2024Article
- Dealing With the Complexity of Effective Population Size in Conservation Practice.Evolutionary applications · 2024Article
- Pitfalls and windfalls of detecting demographic declines using population genetics in long-lived species.Evolutionary applications · 2024Article
- Conservation genetics as a management tool: The five best-supported paradigms to assist the management of threatened species.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Application of Omics Tools in Designing and Monitoring Marine Protected Areas For a Sustainable Blue Economy.Frontiers in genetics · 2022Article
- The estimates of effective population size based on linkage disequilibrium are virtually unaffected by natural selection.PLoS genetics · 2022Article
- Linkage disequilibrium under polysomic inheritance.Heredity · 2022Article
- A brief history and popularity of methods and tools used to estimate micro-evolutionary forces.Ecology and evolution · 2021Review
- The different fates of two Asian horseshoe crab species with different dispersal abilities.Evolutionary applications · 2021Article
- Article
- Population genomics for wildlife conservation and management.Molecular ecology · 2021Review
- Article
- Mapping of Adaptive Traits Enabled by a High-Density Linkage Map for Lake Trout.G3 (Bethesda, Md.) · 2020Article
- Population Genomics Training for the Next Generation of Conservation Geneticists: ConGen 2018 Workshop.The Journal of heredity · 2020Article
- Unbiased Estimation of Linkage Disequilibrium from Unphased Data.Molecular biology and evolution · 2020Article
- Article
- Genomic signatures and correlates of widespread population declines in salmon.Nature communications · 2019Article
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Authors and funding
3 authors.
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No grant is acknowledged in the PubMed record.
Abstract
Estimation of contemporary effective population size (Ne) from linkage disequilibrium (LD) between unlinked pairs of genetic markers has become an important tool in the field of population and conservation genetics. If data pertaining to physical linkage or genomic position are available for genetic markers, estimates of recombination rate between loci can be combined with LD data to estimate contemporary Ne at various times in the past. We extend the well-known, LD-based method of estimating contemporary Ne to include linkage information and show via simulation that even relatively small, recent changes in Ne can be detected reliably with a modest number of single-nucleotide polymorphism (SNP) loci. We explore several issues important to interpretation of the results and quantify the bias in estimates of contemporary Ne associated with the assumption that all loci in a large SNP data set are unlinked. The approach is applied to an empirical data set of SNP genotypes from a population of a marine fish where a recent, temporary decline in Ne is known to have occurred.
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