Evidence map›Paper›PMID 27165737›Full record

ArticleCancer cell2016

Head of the Class: OLIG2 and Glioblastoma Phenotype.

Nalin Leelatian, Rebecca A Ihrie

Abstract readComment
PubMed Publisher
In one paragraph

Article in Cancer cell, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Nalin LeelatianDepartment of Cancer Biology, Vanderbilt University School of Medicine, 761B Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232-6840, USA.
Rebecca A IhrieDepartment of Cancer Biology, Vanderbilt University School of Medicine, 761B Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232-6840, USA; Department of Neurological Surgery, Vanderbilt University School of Medicine, 761B Preston Research Building, 2220 Pierce Avenue, Nashville, TN 37232-6840, USA. Electronic address: rebecca.ihrie@vanderbilt.edu.

Funding

Quantifying Differences in mTOR Activity and Tumor Development Between Neural Stem Cell MicrodomainsR01NS096238 · NINDS · VANDERBILT UNIVERSITY · PI IHRIE, REBECCA A · 2016 to 2020
$1.7M
NINDS NIH HHS R01 NS096238
6 · The paper itself

Abstract

Genomic mapping has driven the classification of glioblastoma into distinct molecular subclasses, but mechanisms that regulate tumor subclass phenotypes are only now emerging. In this issue of Cancer Cell, Lu et al. describe a phenotypic switch from PDGFRA-enriched "proneural" to EGFR-enriched "classical" features in glioblastoma upon ablation of Olig2.

Indexed as

Brain NeoplasmsGlioblastomaHumansPhenotypeTranscription FactorsTranscription Factors

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.