ReviewJournal of clinical neurology (Seoul, Korea)2016
Intracranial Artery Calcification and Its Clinical Significance.
Review in Journal of clinical neurology (Seoul, Korea), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 4 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
49 citing papers in PubMed, 4 syntheses or guidelines pooled it, 81 citations in OpenAlex.
- Shifting the paradigm in intracranial aneurysm detection with deep learning: A diagnostic accuracy meta-analysis and meta-regression.Neurosurgical review · 2026Pooled it
- The role of intracranial artery calcification (IAC) in stroke subtype and risk of vascular events.Journal of stroke and cerebrovascular diseases : the official journal of National Stroke Association · 2023Pooled it
- Intracranial artery calcification as an independent predictor of ischemic stroke: a systematic review and a meta-analysis.BMC neurology · 2023Pooled it
- Association between Periodontitis and Carotid Artery Calcification: A Systematic Review and Meta-Analysis.BioMed research international · 2021Pooled it
- Deep Learning-Assisted Three-Dimensional Segmentation of Vertebrobasilar Artery Calcification in Cone Beam Computed Tomography.Journal of imaging informatics in medicine · 2026Article
- Circadian Blood Pressure Pattern and Microvascular and Macrovascular Cerebral Imaging Burden.Journal of clinical medicine · 2026Article
- The Role and Mechanism of Gut Microbiota and Metabolites in Vascular Calcification.International journal of molecular sciences · 2026Review
- A Comprehensive Review of the Latest Approaches to Managing Hypercholesterolemia: A Comparative Analysis of Conventional and Novel Treatments: Part I.Life (Basel, Switzerland) · 2025Review
- Incidental Calcifications of Carotid and Vertebral Arteries: Frequency and Associations in Pediatric Population.Diagnostics (Basel, Switzerland) · 2025Article
- Exploring the Cerebro-Renovascular Link: Implications of Renal Haemodynamics on Intracranial Arterial Calcification.Aging and disease · 2025Article
- Association of Serum Total Bilirubin Level With Abdominal Aortic Calcification: A Population-Based Cross-Sectional Study.Mediators of inflammation · 2025Article
- The Implications of Aging on Vascular Health.International journal of molecular sciences · 2024Review
- Imaging of intracranial arterial disease: a comparison between MRI and unenhanced CT.Frontiers in radiology · 2024Article
- Risk Factors for Medial and Intimal Intracranial Internal Carotid Artery Calcification in Men and Women with Cardiovascular Disease: The UCC-SMART Study.Cerebrovascular diseases (Basel, Switzerland) · 2024Article
- Relationship between Novel Anthropometric Indices and the Prevalence of Abdominal Aortic Calcification: A Large Cross-Sectional Study.Reviews in cardiovascular medicine · 2023Article
- Association between healthy eating index-2015 and abdominal aortic calcification: A population-based cross-sectional study.Preventive medicine reports · 2023Article
- Intra-Cranial Arterial Calcifications in Hemodialysis Patients.Medicina (Kaunas, Lithuania) · 2023Article
- The 2023 Taiwan Stroke Society Guidelines for the management of patients with intracranial atherosclerotic disease.Journal of the Chinese Medical Association : JCMA · 2023Article
- Correlation Between Intracranial Calcification and Extracranial Stenosis of the Internal Carotid Artery.Cureus · 2023Article
- Stylohyoid Ligament Calcification and Its Association With Dental Diseases.International dental journal · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Intracranial arterial calcification (IAC) is an easily identifiable entity on plain head computed tomography scans. Recent studies have found high prevalence rates for IAC worldwide, and this may be associated with ischemic stroke and cognitive decline. Aging, traditional cardiovascular risk factors, and chronic kidney disease have been found to be associated with IAC. The severity of IAC can be assessed using different visual grading scales or various quantitative methods (by measuring volume or intensity). An objective method for assessing IAC using consistent criteria is urgently required to facilitate comparisons between multiple studies involving diverse populations. There is accumulating evidence from clinical studies that IAC could be utilized as an indicator of intracranial atherosclerosis. However, the pathophysiology underlying the potential correlation between IAC and ischemic stroke-through direct arterial stenosis or plaque stability-remains to be determined. More well-designed clinical studies are needed to explore the predictive values of IAC in vascular events and the underlying pathophysiological mechanisms.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.