ArticleEuropean child & adolescent psychiatry2016
Lead exposure and early child neurodevelopment among children 12-24 months in Kinshasa, the Democratic Republic of Congo.
Article in European child & adolescent psychiatry, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 2 of them syntheses that pooled it.
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Who cites it
10 citing papers in PubMed, 2 syntheses or guidelines pooled it, 17 citations in OpenAlex.
- Neurodevelopmental Outcomes Associated with Early-Life Exposure to Heavy Metals: A Systematic Review.International journal of environmental research and public health · 2025Pooled it
- Heavy metals and neurodevelopment of children in low and middle-income countries: A systematic review.PloS one · 2022Pooled it
- Socio-Emotional, Behavior and Cognitive Disorders Associated with Exposure to Trace Metals: A Cross-Sectional Pilot Study in School-Age Children in Haut-Katanga Province.Children (Basel, Switzerland) · 2025Article
- Potentially toxic metals in umbilical cord blood as a biomarker for passive smoker women.Scientific reports · 2025Article
- Microbiological Analysis and Content of Heavy Metals in Different Candies, Chocolates, and Their Wrappers in Bangladesh.International journal of food science · 2024Article
- Soil-transmitted helminth infection in pregnancy and long-term child neurocognitive and behavioral development: A prospective mother-child cohort in Benin.PLoS neglected tropical diseases · 2021Article
- Environmental exposure to metal mixtures and linear growth in healthy Ugandan children.PloS one · 2020Article
- The Neuroprotective Role of Coenzyme Q10 Against Lead Acetate-Induced Neurotoxicity Is Mediated by Antioxidant, Anti-Inflammatory and Anti-Apoptotic Activities.International journal of environmental research and public health · 2019Article
- Environmental Health Research in Africa: Important Progress and Promising Opportunities.Frontiers in genetics · 2019Review
- Editorial: what are the concerns of a European child and adolescent psychiatrist?European child & adolescent psychiatry · 2016Article
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Childhood lead exposure remains a problem in developing countries, and little is known about its effects on early child neurodevelopment and temperament in the Democratic Republic of Congo (DRC). We, therefore, conducted this study to determine the association between lead exposure and the neurodevelopment and behaviour of children aged 12-24 months in Kinshasa, DRC. A cross-sectional study was conducted between February and June 2012, and parents of 104 children were invited to participate. Blood lead levels (BLLs) of each child were tested using the flame atomic spectrophotometry method. All children were subject to a clinical examination and assessed with two selected early child neurodevelopmental tools, the Gensini-Gavito and the baby characteristics questionnaire, to measure their neurodevelopment and temperament. Detectable BLLs ranged from 1 to 30 μg/dl with a geometric mean of 6.9 (SD 4.8) μg/dl. BLLs at 5-9 and ≥10 μg/dl were significantly associated with the child temperament (p <0.05). Perinatal and maternal factors did not seem to affect early child neurodevelopment and temperament. Children exposed to lead were reported with more temperament difficulties at even blood lead levels <10 μg/dl, suggesting the need for preventive and intervention measures to reduce lead exposure among children in Kinshasa, DRC.
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