Evidence map›Paper›PMID 27165118›Full record

ArticleCurrent genetics2017

fhl1 gene of the fission yeast regulates transcription of meiotic genes and nitrogen starvation response, downstream of the TORC1 pathway.

Emese Pataki, Ronit Weisman, Matthias Sipiczki, Ida Miklos

Abstract read
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In one paragraph

Article in Current genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. TheCells · 2025
    Article
  2. The Product of the Fission YeastInternational journal of molecular sciences · 2023
    Article
  3. Review
  4. Article
  5. Pheromone Response and Mating Behavior in Fission Yeast.Microbiology and molecular biology reviews : MMBR · 2022
    Review
  6. Review
  7. Article
  8. Article
  9. Article
  10. Review
  11. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Emese PatakiDepartment of Genetics and Applied Microbiology, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, 4032, Debrecen, Hungary.
Ronit WeismanDepartment of Natural and Life Sciences, The Open University of Israel, University Road 1, 4353701, Ranana, Israel.
Matthias SipiczkiDepartment of Genetics and Applied Microbiology, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, 4032, Debrecen, Hungary.
Ida MiklosDepartment of Genetics and Applied Microbiology, Faculty of Science and Technology, University of Debrecen, Egyetem tér 1, 4032, Debrecen, Hungary. miklos.ida@science.unideb.hu.
University of Debrecen · HUOpen University of Israel · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Environmental changes, such as nutrient limitation or starvation induce different signal transducing pathways, which require coordinated cooperation of several genes. Our previous data revealed that the fhl1 fork-head type transcription factor of the fission yeast could be involved in sporulation, which was typically induced under poor conditions. Since the exact role of Fhl1 in this process was not known, we wanted to identify its downstream targets and to investigate its possible cooperation with another known regulator of sporulation. Gene expression and Northern blot analysis of the fhl1∆ mutant strain revealed the target genes involved in mating and sporulation. Our results also showed that Fhl1 could regulate nutrient sensing, the transporter and permease genes. Since the majority of these genes belonged to the nitrogen starvation response, the possible cooperation of fhl1 and tor2 was also investigated. Comparison of their microarray data and the expression of fhl1

Indexed as

Gene Expression Regulation, FungalSignal TransductionCluster AnalysisComputational BiologyForkhead Transcription FactorsGene Expression ProfilingGenome-Wide Association StudyMechanistic Target of Rapamycin Complex 1MeiosisMolecular Sequence AnnotationMultiprotein ComplexesMutationNitrogenPromoter Regions, GeneticSchizosaccharomycesSchizosaccharomyces pombe ProteinsFhl1 protein, S pombeForkhead Transcription FactorsMechanistic Target of Rapamycin Complex 1Multiprotein ComplexesNitrogenSchizosaccharomyces pombe ProteinsTOR Serine-Threonine KinasesFork-head transcription factorGene expression analysisNitrogen responseSchizosaccharomyces pombeSporulationTOR pathway

Identifiers

PMID27165118
OpenAlexW2393033092

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.