Evidence map›Paper›PMID 27165057›Full record

ArticleObesity surgery2016

Roux-en-Y Gastric Bypass Surgery on Obstructive Sleep Apnea-Hypopnea Syndrome: Factors Associated with Postoperative Efficacy.

Xiao Jiao, Jianyin Zou, Pin Zhang, Haoyong Yu, Jianzhong Di, Xiaodong Han, Shankai Yin, Hongliang Yi

Abstract read
PubMed Publisher
In one paragraph

Article in Obesity surgery, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 4 pooled it
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 4 syntheses or guidelines pooled it, 11 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Referral of adults with obstructive sleep apnea for surgical consultation: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021
    Pooled it
  4. Pooled it
  5. The Mechanisms of Magnesium in Sleep Disorders.Nature and science of sleep · 2025
    Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Xiao JiaoDepartment of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, 600 Yishan Road, Shanghai, 200233, China.
Jianyin ZouDepartment of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, 600 Yishan Road, Shanghai, 200233, China.
Pin ZhangDepartment of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.
Haoyong YuDepartment of Endocrinology and Metabolism, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai Clinical Center for Diabetes, Shanghai Diabetes Institute, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Key Clinical Center for Metabolic Disease, 600 Yishan Road, Shanghai, 200233, China.
Jianzhong DiDepartment of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.
Xiaodong HanDepartment of General Surgery, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, 200233, China.
Shankai YinDepartment of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, 600 Yishan Road, Shanghai, 200233, China.
Hongliang YiDepartment of Otolaryngology, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Otolaryngology Institute of Shanghai Jiao Tong University, 600 Yishan Road, Shanghai, 200233, China. yihongl@126.com.
Shanghai Jiao Tong University · CNShanghai Sixth People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundBariatric surgery can effectively treat obesity and improve OSAHS. However, the exact underlying mechanisms remain unclear. The objective of this follow-up study is to explore the main factors associated with the efficacy of Roux-en-Y gastric bypass surgery (RYGB) on obstructive sleep apnea-hypopnea syndrome (OSAHS).

methodsA total of 39 OSAHS patients with obesity and type 2 diabetes mellitus (T2DM) who had received RYGB surgery were recruited. A polysomnography test was carried out in all subjects before surgery and postoperative 6 to 12 months, and the following tests were performed: fasting glucose, lipid profile, electrolyte levels, and liver and kidney function tests. The paired Student's t test, Pearson test, Spearman correlation test, and multiple linear regression analysis were used to explore the effects of RYGB surgery on these indices and investigate the main factors associated with postoperative efficacy.

resultsRYGB surgery significantly lowered the apnea-hypopnea index (AHI), body mass index (BMI), and concentrations of total albumin, prealbumin, retinol-binding protein, total cholesterol, triglycerides, fasting blood glucose, albumin, and C-reactive protein, while postoperative blood magnesium levels were significantly increased (p < 0.05). Changes in the AHI (delta AHI) were correlated with delta BMI (r = 0.408, p = 0.010) and delta prealbumin levels (r = 0.495, p = 0.001). However, no significant correlation was found between delta BMI and delta prealbumin. The delta AHI were assessed by multiple linear analysis as follows: delta AHI = 0.105 × (delta prealbumin) + 1.509 × (delta BMI) + 1.006.

conclusionsRYGB is an effective therapeutic option for OSAHS patients with obesity and T2DM; the potential factors associated with postoperative efficacy include changes in BMI and prealbumin levels.

Indexed as

AdultBody Mass IndexDiabetes Mellitus, Type 2FemaleFollow-Up StudiesGastric BypassHumansMaleMiddle AgedObesity, MorbidPolysomnographyPostoperative PeriodSleep Apnea, ObstructiveBariatric surgeryDiabetes mellitusObesityObstructive sleep apnea–hypopnea syndromePrealbumin

Identifiers

PMID27165057
OpenAlexW2348126920

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.