ArticleHealth and quality of life outcomes2016
Development and validation of quality of life scale of nasopharyngeal carcinoma patients: the QOL-NPC (version 2).
Article in Health and quality of life outcomes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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12 citing papers in PubMed, 17 citations in OpenAlex.
- Development and validation of the symptom assessment scale for patients with nasopharyngeal cancer undergoing radiotherapy.Asia-Pacific journal of oncology nursing · 2025Article
- Effects of psychological support intervention on patients with nasopharyngeal carcinoma undergoing radiotherapy.Pakistan journal of medical sciences · 2024Article
- Quality of life in patients with nasopharyngeal carcinoma receiving IMRT vs IMPT: a multicenter prospective longitudinal study.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024Article
- Oral-Functioning Questionnaires in Patients with Head and Neck Cancer: A Scoping Review.Journal of clinical medicine · 2023Article
- Evaluation of Sinonasal Outcome Test (SNOT-22) Domains in the Assessment of the Quality of Life in Patients with Nasopharyngeal Carcinoma.Cancer management and research · 2023Article
- Development and Validation of the Oral Health-Related Self-Efficacy Scale for Cancer Patients.Journal of cancer education : the official journal of the American Association for Cancer Education · 2021Article
- Development and validation of immune inflammation-based index for predicting the clinical outcome in patients with nasopharyngeal carcinoma.Journal of cellular and molecular medicine · 2020Article
- Development of a Diagnostic Questionnaire for Damp Phlegm Pattern and Blood Stasis Pattern in Coronary Heart Disease Patients (CHD-DPBSPQ).Evidence-based complementary and alternative medicine : eCAM · 2019Article
- Expert Consensus of Syndrome Differentiation for Phlegm Turbidity Syndrome for Coronary Heart Disease.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Development of a Traditional Chinese Medicine Syndrome-Specific Scale for Ulcerative Colitis: The Large Intestine Dampness-Heat Syndrome Questionnaire.Evidence-based complementary and alternative medicine : eCAM · 2018Article
- Validation of the Chinese version of functional assessment of anorexia-cachexia therapy (FAACT) scale for measuring quality of life in cancer patients with cachexia.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2017Article
- Concurrent chemoradiotherapy degrades the quality of life of patients with stage II nasopharyngeal carcinoma as compared to radiotherapy.Oncotarget · 2017Article
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim was to develop and validate the quality of life scale for nasopharyngeal carcinoma (NPC) patients, the QOL-NPC (version 2), a specific instrument to measure quality of life for NPC patients.
methodsThe QOL-NPC was developed and validated according to standard procedures. The patients were assessed using the QOL-NPC, FACT-G, and FACT-H&N. Classical test theory was used to evaluate the reliability, validity, and responsiveness of the QOL-NPC.
resultsA total of 487 patients (97.4 %) completed the questionnaire. The QOL-NPC comprised four domains, as follows: physical function (eight items); psychological function (five items); social function (five items); and side effects (eight items). All of the items had a lower proportion of missing data. Cronbach's alpha values of the domains ranged from 0.72 to 0.84. The split-half reliability coefficients ranged from 0.77 to 0.84. All of the intra-class correlation coefficients were > 0.8. The normed fit index, non-normed fit index, and comparative fit index were >0.89. The root mean square error of approximation was 0.097, with a 90 % confidence interval (0.093, 0.100). The domain scores of the QOL-NPC were significantly correlated with the FACT-G and FACT-H&N (P < 0.05). All of the domain scores of patients using different amounts of radiotherapy were significantly different (P < 0.001). All domain scores decreased at the completion of radiotherapy, with effect sizes ranging from -0.82 to -0.22.
conclusionsThe QOL-NPC is valid for measuring QOL with good reliability, validity, and responsiveness. The QOL-NPC is recommended to measure the QOL for Chinese NPC patients.
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