ArticleCell and tissue research2016
Exclusion of dysfunctional mitochondria from Balbiani body during early oogenesis of Thermobia.
Article in Cell and tissue research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
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Who cites it
24 citing papers in PubMed.
- Oocyte Aging as a Systems-Level Failure of Cellular Quality Control Networks: Insights from Comparative Biology.Biology · 2026Review
- Mitochondrial DNA Inheritance and Germline Purifying Selection: Insights FromAnnual review of genetics · 2026Review
- Analysis of Bush Cricket Oogenesis Provides an Insight into the Function and Anagenesis of an Enigmatic Organelle Assemblage: The Balbiani Body.Results and problems in cell differentiation · 2026Article
- Early female germline development inProceedings of the National Academy of Sciences of the United States of America · 2025Article
- Germ plasm dynamics during oogenesis and early embryonic development in Xenopus and zebrafish.Molecular reproduction and development · 2024Review
- Balbiani body of basal insects is potentially involved in multiplication and selective elimination of mitochondria.Scientific reports · 2024Article
- Female Germline Cysts in Animals: Evolution and Function.Results and problems in cell differentiation · 2024Review
- The constructive and destructive impact of autophagy on both genders' reproducibility, a comprehensive review.Autophagy · 2023Review
- The three-dimensional conformation and activity of mitochondria in syncytial male germ line-cysts of medicinal leeches.Cell and tissue research · 2023Article
- Tools to analyze the organization and formation of the germline cyst in zebrafish oogenesis.Development (Cambridge, England) · 2023Article
- Effects of adverse fertility-related factors on mitochondrial DNA in the oocyte: a comprehensive review.Reproductive biology and endocrinology : RB&E · 2023Review
- Gametogenesis: Exploring an Endogenous Rejuvenation Program to Understand Cellular Aging and Quality Control.Annual review of genetics · 2022Review
- All for one: changes in mitochondrial morphology and activity during syncytial oogenesis†.Biology of reproduction · 2022Article
- Stage Specific Transcriptomic Analysis and Database for Zebrafish Oogenesis.Frontiers in cell and developmental biology · 2022Article
- The need for high-quality oocyte mitochondria at extreme ploidy dictates mammalian germline development.eLife · 2021Article
- Mitonuclear Coevolution, but not Nuclear Compensation, Drives Evolution of OXPHOS Complexes in Bivalves.Molecular biology and evolution · 2021Article
- Cellular quality control during gametogenesis.Experimental cell research · 2020Review
- Mitochondrial DNA segregation and replication restrict the transmission of detrimental mutation.The Journal of cell biology · 2020Article
- Review
- Morphology of Mitochondria in Syncytial Annelid Female Germ-Line Cyst Visualized by Serial Block-Face SEM.International journal of cell biology · 2020Article
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Authors and funding
5 authors.
Funding
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Abstract
Oocytes of many invertebrate and vertebrate species contain a characteristic organelle complex known as the Balbiani body (Bb). Until now, three principal functions have been ascribed to this complex: delivery of germ cell determinants and localized RNAs to the vegetal cortex/posterior pole of the oocyte, transport of the mitochondria towards the germ plasm, and participation in the formation of lipid droplets. Here, we present the results of a computer-aided 3D reconstruction of the Bb in the growing oocytes of an insect, Thermobia domestica. Our analyses have shown that, in Thermobia, the central part of each fully developed Bb comprises a single intricate mitochondrial network. This "core" network is surrounded by several isolated bean-shaped mitochondrial units that display lowered membrane potential and clear signs of degeneration. In light of the above results and recent theoretical models of mitochondrial quality control, the role of the Bb is discussed. We suggest that, in addition to the aforementioned functions, the Bb is implicated in the selective elimination of dysfunctional mitochondria during oogenesis.
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