Evidence map›Paper›PMID 27164702›Full record

ArticleNeurology2016

Progressive neurologic disorder: Initial manifestation of hemophagocytic lymphohistiocytosis.

Claire Murphy, Sira Nanthapisal, Kimberly Gilmour, Sue Laurent, Felice D'Arco, Cheryl Hemingway, Paul Brogan, Despina Eleftheriou

Abstract readCase Reports
In one paragraph

Article in Neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Hemophagocytic LymphohistiocytosisBalkan medical journal · 2022
    Article
  5. Article
  6. Review
  7. Review
  8. Review
  9. Article
  10. Two Brothers with AtypicalFrontiers in immunology · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Claire MurphyFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK. Claire.Murphy.13@ucl.ac.uk.
Sira NanthapisalFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.
Kimberly GilmourFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.
Sue LaurentFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.
Felice D'ArcoFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.
Cheryl HemingwayFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.
Paul BroganFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.
Despina EleftheriouFrom the Infection, Immunity, Inflammation and Physiological Medicine Programme (C.M., S.N., P.B., D.E.), University College London Institute of Child Health, UK; Faculty of Medicine (S.N.), Thammasat University, Thailand; Immunology (K.G.), Neuroradiology Department (F.D.), and Neurology Department (C.H.), Great Ormond Street Hospital NHS Foundation Trust, London; and Paediatric Department (S.L.), Royal Free Hospital NHS Foundation Trust, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Nervous System DiseasesAdolescentDisease ProgressionFemaleHumansLymphohistiocytosis, HemophagocyticMagnetic Resonance ImagingMembrane ProteinsMutationMembrane ProteinsUNC13D protein, human

Identifiers

PMID27164702
PMCPMC4891214

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.