Evidence map›Paper›PMID 27164692›Full record

Observational studyNeurology2016

Better outcomes for hospitalized patients with TIA when in stroke units: An observational study.

Dominique A Cadilhac, Joosup Kim, Natasha A Lannin, Christopher R Levi, Helen M Dewey, Kelvin Hill, Steven Faux, Nadine E Andrew, Monique F Kilkenny, Rohan Grimley and 6 more

Open access · greenAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Neurology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
4.1field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Factors influencing self-reported anxiety or depression following stroke or TIA using linked registry and hospital data.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2018
    Article
  9. Using emergency trauma team activations to measure trauma activity and injury severity: 10 years of experience using an Australian major trauma centre registry.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2018
    Article
  10. Review
  11. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

16 authors at 11 institutions in 1 country.

Dominique A CadilhacFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia. dominique.cadilhac@monash.edu.
Joosup KimFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Natasha A LanninFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Christopher R LeviFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Helen M DeweyFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Kelvin HillFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Steven FauxFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Nadine E AndrewFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Monique F KilkennyFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Rohan GrimleyFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Amanda G ThriftFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Brenda GrabschFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Sandy MiddletonFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Craig S AndersonFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Geoffrey A DonnanFrom Stroke and Ageing Research, School of Clinical Sciences at Monash Health (D.A.C., J.K., N.E.A., M.F.K., A.G.T.), and Eastern Health Clinical School (H.M.D.), Monash University, Victoria; Stroke Division (D.A.C., J.K., H.M.D., N.E.A., M.F.K., B.G., G.A.D.), Florey Institute of Neuroscience and Mental Health, Heidelberg, Victoria; La Trobe University (N.A.L.), Victoria; University of Newcastle (C.R.L.), New South Wales; National Stroke Foundation (K.H.), Victoria; St Vincent's Health Australia (Sydney) (S.F., S.M.), New South Wales; Sunshine Coast Clinical School (R.G.), The University of Queensland; Australian Catholic University (S.M.), New South Wales; The George Institute for Global Health (C.S.A.), Royal Prince Alfred Hospital, Camperdown, New South Wales; and Central Clinical School (C.S.A.), The University of Sydney, New South Wales, Australia.
Australian Stroke Clinical Registry Consortium
Royal Prince Alfred Hospital · AUFlorey Institute of Neuroscience and Mental Health · AUSt Vincent's Health · AUMonash University · AUUniversity of Newcastle Australia · AUUniversity of Queensland · AUAustralian Catholic University · AUEastern Health · AULa Trobe University · AUMonash Health · AUNational Stroke Foundation · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate differences in management and outcomes for patients admitted to the hospital with TIA according to care on a stroke unit (SU) or alternate ward setting up to 180 days post event.

methodsTIA admissions from 40 hospitals participating in the Australian Stroke Clinical Registry during 2010-2013 were assessed. Propensity score matching was used to assess outcomes by treatment group including Cox proportional hazards regression to compare survival differences and other appropriate multivariable regression models for outcomes including health-related quality of life and readmissions.

resultsAmong 3,007 patients with TIA (mean age 73 years, 54% male), 1,110 pairs could be matched. Compared to management elsewhere in hospitals, management in an SU was associated with improved cumulative survival at 180 days post event (hazard ratio 0.57, 95% confidence interval 0.35-0.94; p = 0.029), despite not being statistically significant at 90 days (hazard ratio 0.66, 95% confidence interval 0.33-1.31; p = 0.237). Overall, there were no differences for being discharged on antihypertensive medication or with a care plan, and the 90- to 180-day self-reported outcomes between these groups were similar. In subgroup analyses of 461 matched pairs treated in hospitals in one Australian state (Queensland), patients treated in an SU were more often prescribed aspirin within 48 hours (73% vs 62%, p < 0.001) and discharged on antithrombotic medications (84% vs 71%, p < 0.001) than those not treated in an SU.

conclusionsHospitalized patients with TIA managed in SUs had better survival at 180 days than those treated in alternate wards, potentially through better management, but further research is needed.

Indexed as

HospitalizationAgedAged, 80 and overAustraliaFemaleHumansIschemic Attack, TransientMaleMiddle AgedMultivariate AnalysisPatient Reported Outcome MeasuresProportional Hazards ModelsQuality of LifeRegistriesSelf ReportStroke

Identifiers

PMID27164692
PMCPMC4891210
OpenAlexW2346285081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.