Evidence map›Paper›PMID 27164192›Full record

ArticleSubstance abuse

Opioid overdose prevention through pharmacy-based naloxone prescription program: Innovations in health care delivery.

Amy Bachyrycz, Shikhar Shrestha, Barry E Bleske, Dale Tinker, Ludmila N Bakhireva

Abstract read
In one paragraph

Article in Substance abuse. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Naloxone availability in independent community pharmacies in Georgia, 2019.Substance abuse treatment, prevention, and policy · 2021
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. The opioid overdose epidemic: opportunities for pharmacists.Substance abuse and rehabilitation · 2017
    Article
  13. Article
  14. PHArmacists' perspective oN the Take hOme naloxone prograM (The PHANTOM Study).Canadian pharmacists journal : CPJ = Revue des pharmaciens du Canada : RPC
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Amy Bachyrycza Department of Pharmacy Practice and Administrative Sciences , College of Pharmacy, University of New Mexico , Albuquerque , New Mexico , USA.
Shikhar Shresthaa Department of Pharmacy Practice and Administrative Sciences , College of Pharmacy, University of New Mexico , Albuquerque , New Mexico , USA.
Barry E Bleskea Department of Pharmacy Practice and Administrative Sciences , College of Pharmacy, University of New Mexico , Albuquerque , New Mexico , USA.
Dale Tinkerc New Mexico Pharmacists Association , New Mexico , USA.
Ludmila N Bakhirevaa Department of Pharmacy Practice and Administrative Sciences , College of Pharmacy, University of New Mexico , Albuquerque , New Mexico , USA.

Funding

UNM HSC Clinical and Translational Science CenterUL1TR001449 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI CAMPEN, MATTHEW J, PANDHI, NANCY · 2015 to 2024
$36.9M
University of New Mexico Clinical and Translational Science CenterUL1TR000041 · NCATS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LARSON, RICHARD S · 2012 to 2014
$9.8M
The effect of the COVID-19 pandemic on alcohol use and psycho-somatic health in pregnant and postpartum women with intersecting vulnerabilities.R01AA021771 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BAKHIREVA, LUDMILA NICOLE · 2013 to 2022
$6.5M
Interactive Effect of Environmental Exposures and Alcohol in the Navajo Birth CohR15AA022242 · NIAAA · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI BAKHIREVA, LUDMILA NICOLE, LEWIS, JOHNNYE L · 2013 to 2013
$422k
NCATS NIH HHS UL1 TR000041NCATS NIH HHS UL1 TR001449NIAAA NIH HHS R01 AA021771NIAAA NIH HHS R15 AA022242
6 · The paper itself

Abstract

backgroundGiven that opioid misuse/abuse and opioid overdose have reached epidemic proportions in the United States, expansion of naloxone access programs are desperately needed. The objective of this study was to describe emerging trends in naloxone rescue kit (NRK) prescription patterns by pharmacists in New Mexico as an example of a unique health care delivery system.

methodsThe study presents cross-sectional analysis of the data on NRK prescriptions by pharmacists who received naloxone pharmacist prescriptive authority certification since 2013. Data were obtained from the Prevention of Opioid Overdose by New Mexico Pharmacists (POINt-Rx) Registry, maintained by the University of New Mexico and the New Mexico Pharmacists Association.

resultsSince 2013, 133 NRKs prescribed by pharmacists have been reported to the POINt-Rx Registry. The mean age of the patients was 41.5 ± 12.0 years (range: 19-67 years), and 60.2% were female participants. Only 11.3% of the prescriptions were from pharmacists practicing in rural/mixed urban-rural areas. The majority of NRKs (89.5%) were first-time prescriptions. The most common reason for a NRK prescription was patient's request (56.4%), followed by a pharmacist's prescription of NRK due to high dose of prescription opioids (28.6%) and history of opioid misuse/abuse (15.0%). In addition to opioids, other frequently reported substances included alcohol (9.2%) and benzodiazepines (10.8%). More than a third of patients (38.5%) reported polysubstance use in the previous 72 hours.

conclusionsThese results indicate that patients at risk of opioid overdose might feel comfortable soliciting NRKs from a pharmacist. Participation of pharmacists in rural areas in the naloxone prescriptive authority highlight the opportunity for this novel health care delivery model in underserved areas; however, the program is clearly underutilized in these areas. Such a model can provide expanded patient access in community practices, whereas systematic efforts for uptake of the program by policy makers, communities, and pharmacists continue to be needed nationwide.

Indexed as

Pharmaceutical ServicesAdultAgedCross-Sectional StudiesDrug OverdoseDrug PrescriptionsFemaleHumansMaleMiddle AgedNaloxoneNarcotic AntagonistsNew MexicoOpioid-Related DisordersYoung AdultNaloxoneNarcotic AntagonistsCommunity pharmacydelivery of health carenaloxoneopioids

Identifiers

PMID27164192
PMCPMC5623593

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.