Evidence map›Paper›PMID 27163960›Full record

ArticleAnnals of surgery2017

Chronic Opioid Usage in Surgical Patients in a Large Academic Center.

Xueying Jiang, Margaret Orton, Rui Feng, Erik Hossain, Neil R Malhotra, Eric L Zager, Renyu Liu

Registry-linked trialAbstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Annals of surgery, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03469310 (Minimizing Narcotic Analgesics After Thyroid or Parathyroid Surgery), which is not on this map. Cited by 74 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
74citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03469310 phase4completednot on this mapstarted 2018, after this paper: background citation

Minimizing Narcotic Analgesics After Thyroid or Parathyroid Surgery

TypeinterventionalSponsorMinerva A Romero ArenasRan2018 to 2020Enrolled126ConditionsThyroid Cancer, Thyroid Nodule, Thyroid Neoplasms, Thyroid GoitreArmsAcetaminophen 500Mg Cap, Tylenol #3 Oral Tablet, Tramadol
3 · Its place in the literature

Who cites it

74 citing papers in PubMed, 4 syntheses or guidelines pooled it.

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  17. Effect of Multidisciplinary Transitional Pain Service on Health Care Use and Costs Following Orthopedic Surgery.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2023
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14 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Xueying Jiang*Department of Anesthesiology, Beijing Tongren Hospital, Capital Medical University, Beijing, China †Department of Anesthesiology and Critical Care, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA ‡Department of Biostatistics and Epidemiology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA §EPIC Data Report, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA ||Department of Neurosurgery, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA.
Margaret Orton
Rui Feng
Erik Hossain
Neil R Malhotra
Eric L Zager
Renyu Liu

Funding

Water soluble variants of the human mu opioid receptorR01GM111421 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI LIU, RENYU · 2014 to 2018
$1.7M
Structural Approaches for Understanding Opioid and ??-Receptor InteractionsK08GM093115 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI LIU, RENYU · 2010 to 2013
$505k
NIGMS NIH HHS K08 GM093115NIGMS NIH HHS R01 GM111421
6 · The paper itself

Abstract

objectiveThe objective of this study is to investigate the prevalence and disparity of chronic opioid usage in surgical patients and the potential risk factors associated with chronic opioid usage.

backgroundChronic opioid usage is common in surgical patients; however, the characteristics of opioid usage in surgical patients is unclear. In this study, we hypothesize that the prevalence of chronic opioid usage in surgical patients is high, and that significant disparities may exist among different surgical populations.

methodsData of opioid usage in outpatients among different surgical services were extracted from the electronic medical record database. Patient demographics, clinical characteristics of sex, age, race, body mass index (BMI), specialty visited, duration of opioid use, and opioid type were collected. Chronic opioid users were defined as patients who had been recorded as taking opioids for at least 90 days determined by the first and last visit dates under opioid usage during the investigation.

resultsThere were 79,123 patients included in this study. The average prevalence is 9.2%, ranging from 4.4% to 23.8% among various specialties. The prevalence in orthopedics (23.8%), neurosurgery (18.7%), and gastrointestinal surgery (14.4%) ranked in the top three subspecialties. Major factors influencing chronic opioid use include age, Ethnicitiy, Subspecialtiy, and multiple specialty visits. Approximately 75% of chronic users took opioids that belong to the category II Drug Enforcement Administration classification.

conclusionsOverall prevalence of chronic opioid usage in surgical patients is high with widespread disparity among different sex, age, ethnicity, BMI, and subspecialty groups. Information obtained from this study provides clues to reduce chronic opioid usage in surgical patients.

Indexed as

Academic Medical CentersAdultAgedAged, 80 and overAge FactorsAnalgesics, OpioidChronic PainConfidence IntervalsCross-Sectional StudiesDatabases, FactualDrug Administration ScheduleFemaleHumansMaleMiddle AgedOdds RatioAnalgesics, Opioid

Identifiers

PMID27163960
PMCPMC5557500

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.