ReviewAmerican journal of respiratory cell and molecular biology2016
Mouse Modeling of Obese Lung Disease. Insights and Caveats.
Review in American journal of respiratory cell and molecular biology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
12 citing papers in PubMed, 19 citations in OpenAlex.
- A Short-Term High-Sugar Diet Induces Glucose Intolerance, Visceral Adipose Tissue Inflammation, and Exacerbates Experimental Allergic Asthma.Nutrients · 2026Article
- Examination of the exposome in an animal model: The impact of high fat diet and rat strain on local and systemic immune markers following occupational welding fume exposure.Toxicology and applied pharmacology · 2023Article
- Airway immune response in the mouse models of obesity-related asthma.Frontiers in physiology · 2022Review
- Aberrant pulmonary immune response of obese mice to periodontal infection.Open life sciences · 2022Article
- The Role of Obesity in the Immunopathogenesis of COVID-19 Respiratory Disease and Critical Illness.American journal of respiratory cell and molecular biology · 2021Review
- IL-33, diet-induced obesity, and pulmonary responses to ozone.Respiratory research · 2020Article
- Fatty acid synthase downregulation contributes to acute lung injury in murine diet-induced obesity.JCI insight · 2019Article
- Future Research Directions in Pneumonia. NHLBI Working Group Report.American journal of respiratory and critical care medicine · 2018Article
- Integrative Physiology of Pneumonia.Physiological reviews · 2018Review
- Inflammation Gets on the Lung's Nerves: IL-17 and Neuroendocrine Cells Mediate Ozone Responses in Obesity.American journal of respiratory cell and molecular biology · 2018Article
- Obesogenic diets alter metabolism in mice.PloS one · 2018Article
- Chair's Summary: Obesity and Associated Changes in Metabolism, Implications for Lung Diseases.Annals of the American Thoracic Society · 2017Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author at 1 institution in 1 country.
Funding
Abstract
As the obesity epidemic has worsened, its impact on lung health and disease has become progressively evident. The interactions between obesity and the accompanying metabolic syndrome and diseases such as asthma, pneumonia, and acute respiratory distress syndrome (ARDS) have proven complex and often counterintuitive in human studies. Hence, there is a growing need for relevant experimental approaches to understand the interactions between obesity and the lung. To this end, researchers have increasingly exploited mouse models combining both obesity and lung diseases, including ARDS, pneumonia, and asthma. Such models have both complemented and advanced the understanding we have gained from clinical studies and have allowed elegant dissections of obesity's effects on the pathogenesis of lung disease. Yet these models come with several critically important caveats that we must reflect on when interpreting their results.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.