Evidence map›Paper›PMID 27163657›Full record

SynthesisHuman vaccines & immunotherapeutics2016

Determinants of European parents' decision on the vaccination of their children against measles, mumps and rubella: A systematic review and meta-analysis.

Garden Tabacchi, Claudio Costantino, Giuseppe Napoli, Valentina Marchese, Manuela Cracchiolo, Alessandra Casuccio, Francesco Vitale, The Esculapio Working Group

Abstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 47 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
47citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

47 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  6. Health literacy and vaccination: A systematic review.Human vaccines & immunotherapeutics · 2018
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  19. A Study Prevalence of Congenital Rubella Syndrome Cases Before and After Rubella Vaccination Campaign.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Garden Tabacchia Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
Claudio Costantinoa Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
Giuseppe Napolia Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
Valentina Marchesea Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
Manuela Cracchioloa Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
Alessandra Casuccioa Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
Francesco Vitalea Department of Sciences for Health Promotion and Mother-Child Care "G.D'Alessandro ", University of Palermo , Palermo , Italy.
The Esculapio Working Group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Low measles, mumps and rubella (MMR) immunization levels in European children highlight the importance of identifying determinants of parental vaccine uptake to implement policies for increasing vaccine compliance. The aim of this paper is to identify the main factors associated with partial and full MMR vaccination uptake in European parents, and combine the different studies to obtain overall quantitative measures. This activity is included within the ESCULAPIO project, funded by the Italian Ministry of Health. ORs and CIs were extracted, sources of heterogeneity explored and publication bias assessed. Forty-five papers were retrieved for the qualitative study, 26 of which were included in the meta-analysis. The following factors were associated with lower MMR vaccine uptake: misleading knowledge, beliefs and perceptions on vaccines (OR 0.57, CI 0.37-0.87); negative attitudes and behaviors toward vaccination (OR 0.71, CI 0.52-0.98); demographic characteristics, such as different ethnicity in Southern populations (OR 0.44, CI 0.31-0.61), higher child's age (OR 0.80, CI 0.76-0.85); low socio-economic status (OR 0.64, CI 0.51-0.80), especially low income (OR 0.39, CI 0.25-0.60) and education (OR 0.64, CI 0.48-0.84), high number of children (OR 0.54, CI 0.42-0.69), irregular marital status (OR 0.80, CI 0.66-0.96). The factors explaining heterogeneity were country location, administration modality, collection setting and responses reported on MMR alone or in combination. Findings from this study suggest policy makers to focus communication strategies on providing better knowledge, correct beliefs and perceptions on vaccines, and improving attitudes and behaviors in parents; and to target policies to people of ethnic minority from Southern Europe, low educated and deprived, with higher number of children and non-married marital status.

Indexed as

ParentsEuropeHealth Knowledge, Attitudes, PracticeHumansMeaslesMeasles-Mumps-Rubella VaccineMumpsPatient Acceptance of Health CareRubellaVaccinationMeasles-Mumps-Rubella Vaccinedeterminantmeaslesmumps and rubellaparentsuptakevaccine

Identifiers

PMID27163657
PMCPMC4964810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.