Evidence map›Paper›PMID 27162961›Full record

ReviewACS central science2015

Biological Responses to Engineered Nanomaterials: Needs for the Next Decade.

Catherine J Murphy, Ariane M Vartanian, Franz M Geiger, Robert J Hamers, Joel Pedersen, Qiang Cui, Christy L Haynes, Erin E Carlson, Rigoberto Hernandez, Rebecca D Klaper and 2 more

Abstract readReview
In one paragraph

Review in ACS central science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Structure and Zeta Potential of Gold Nanoparticles with Coronas of Varying Size and Composition.The journal of physical chemistry. C, Nanomaterials and interfaces · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
  11. Virus-like Particles: Fundamentals and Biomedical Applications.International journal of molecular sciences · 2022
    Review
  12. Article
  13. Article
  14. Membrane Phase Drives the Assembly of Gold Nanoparticles on Biomimetic Lipid Bilayers.The journal of physical chemistry. C, Nanomaterials and interfaces · 2022
    Article
  15. Article
  16. Review
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Catherine J MurphyDepartment of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
Ariane M VartanianDepartment of Chemistry, University of Illinois at Urbana-Champaign , 600 South Mathews Avenue, Urbana, Illinois 61801, United States.
Franz M GeigerDepartment of Chemistry, Northwestern University , 2145 Sheridan Road, Evanston, Illinois 60208, United States.
Robert J HamersDepartment of Chemistry, University of Wisconsin-Madison , 1101 University Avenue, Madison, Wisconsin 53706, United States.
Joel PedersenDepartment of Chemistry, University of Wisconsin-Madison , 1101 University Avenue, Madison, Wisconsin 53706, United States.
Qiang CuiDepartment of Chemistry, University of Wisconsin-Madison , 1101 University Avenue, Madison, Wisconsin 53706, United States.
Christy L HaynesDepartment of Chemistry, University of Minnesota , 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States.
Erin E CarlsonDepartment of Chemistry, University of Minnesota , 207 Pleasant Street SE, Minneapolis, Minnesota 55455, United States.
Rigoberto HernandezSchool of Chemistry and Biochemistry, Georgia Institute of Technology , 901 Atlantic Drive, Atlanta, Georgia 30332, United States.
Rebecca D KlaperSchool of Freshwater Sciences, University of Wisconsin-Milwaukee , 600 East Greenfield Avenue, Milwaukee, Wisconsin 53204, United States.
Galya OrrEnvironmental Molecular Sciences Laboratory, Pacific Northwest National Laboratory , 3335 Innovation Boulevard, Richland, Washington 99352, United States.
Ze'ev RosenzweigDepartment of Chemistry, University of Maryland, Baltimore County , 1000 Hilltop Circle, Baltimore, Maryland 21250, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The interaction of nanomaterials with biomolecules, cells, and organisms is an enormously vital area of current research, with applications in nanoenabled diagnostics, imaging agents, therapeutics, and contaminant removal technologies. Yet the potential for adverse biological and environmental impacts of nanomaterial exposure is considerable and needs to be addressed to ensure sustainable development of nanomaterials. In this Outlook four research needs for the next decade are outlined: (i) measurement of the chemical nature of nanomaterials in dynamic, complex aqueous environments; (ii) real-time measurements of nanomaterial-biological interactions with chemical specificity; (iii) delineation of molecular modes of action for nanomaterial effects on living systems as functions of nanomaterial properties; and (iv) an integrated systems approach that includes computation and simulation across orders of magnitude in time and space.

Identifiers

PMID27162961
PMCPMC4827556

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.