ReviewAnnals of translational medicine2016
Patient specific instrumentation in total knee arthroplasty: a state of the art.
Review in Annals of translational medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 3 syntheses or guidelines pooled it, 85 citations in OpenAlex.
- No difference between CT- and MRI-based patient-specific instrumentation for total knee arthroplasty: an updated systematic review and meta-analysis.Frontiers in bioengineering and biotechnology · 2025Pooled it
- Are There Differences in Accuracy or Outcomes Scores Among Navigated, Robotic, Patient-specific Instruments or Standard Cutting Guides in TKA? A Network Meta-analysis.Clinical orthopaedics and related research · 2020Pooled it
- Patient-Specific or Conventional Instrumentations: A Meta-analysis of Randomized Controlled Trials.BioMed research international · 2020Pooled it
- No differences in mid-term survival and clinical outcome between CT- and MRI-based patient-specific instrumentation for total knee arthroplasty, a randomized controlled trial.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2024Trial
- Restoring tibial obliquity for kinematic alignment in total knee arthroplasty: conventional versus patient-specific instrumentation.Archives of orthopaedic and trauma surgery · 2023Trial
- Single-use, patient-specific instrumentation technology in knee arthroplasty: a comparative study between standard instrumentation and PSI efficiency system.Musculoskeletal surgery · 2020Trial
- Comparable clinical outcome and implant longevity after CT- or MRI-based patient-specific instruments for total knee arthroplasty: a 2-year follow-up of a RCT.Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA · 2020Trial
- A historical journey through total knee arthroplasty: the evolutionary milestones.International orthopaedics · 2026Review
- Robotic-Assisted Total Knee Arthroplasty: Current Evidence on PROMs, Functional Outcomes, Neuromotor Recovery, and Complications-A Narrative Review.Medicina (Kaunas, Lithuania) · 2026Review
- Quantifying the Contribution of Bone Morphology to Implant Selection in Shoulder Arthroplasty Using CT-Based Deep Learning.Bioengineering (Basel, Switzerland) · 2026Article
- The effect of using patient-specific guides for total knee replacement without hardware removal in complex post-traumatic arthritis: an in-vitro study.Biomedical engineering online · 2026Article
- Total knee arthroplasty with simultaneous triplanar osteotomy of the distal femur using patient-specific instrumentation : A case report.Orthopadie (Heidelberg, Germany) · 2026Article
- Higher cost, comparable outcomes: A health economic evaluation of patient-specific instrumentation vs. conventional instrumentation for total knee arthroplasty in a Dutch aging population.Journal of experimental orthopaedics · 2025Article
- Comparison between robotic-assisted and navigation-assisted total knee arthroplasty shows comparable outcomes: A systematic review and meta-analysis.Journal of orthopaedics · 2025Review
- Advancements in Total Knee Arthroplasty over the Last Two Decades.Journal of clinical medicine · 2025Review
- Patient-Specific Cutting Guides for Alignment-Correcting Osteotomy About the Knee: A Study of Accuracy, Cost, and Surgical and Fluoroscopic Safety.Orthopaedic journal of sports medicine · 2025Article
- Patient-specific instrumentation in primary total shoulder arthroplasty: a meta-analysis of clinical outcomes.Clinics in shoulder and elbow · 2025Article
- Accuracy of total knee arthroplasty using hospital-based 3D printed patient-specific instrumentation: A radiology research.Journal of orthopaedics · 2025Article
- Femoral resection accuracy and precision in manual caliper-verified kinematic alignment total knee arthroplasty.Journal of experimental orthopaedics · 2025Article
- Trends in adoption of robotics in arthroplasty: an analysis of the Indian landscape.Journal of robotic surgery · 2025Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patient specific instrumentation (PSI) is a modern technique in total knee arthroplasty (TKA) aiming to facilitate the implant of the prosthesis. The customized cutting blocks of the PSI are generated from pre-operative three-dimensional model, using computed tomography (CT) or magnetic resonance imaging (MRI). A correct surgical plan is mandatory for a good surgical implant. The PSI guide takes into account any slight deformities or osteophytes and applies preoperative planning for bone resection, using the pre-determined implant size, position, and rotation. The apparent benefits of this technology are that neutral postoperative alignment is more reproducible, surgical time is decreased, and the entire procedure results more efficient and cost-effective. The use of PSI is indicated when advanced osteoarthritis, severe pain, and limited function/walking ability are present, such as in a standard instrumentation TKA. In addition to that, PSI finds its indication when intra-medullary guides cannot be used. For example, when there is a post-traumatic femoral deformity. Large debates have taken place about this topic during the last years and, at the moment, there is no consensus in literature regarding the accuracy and reliability of PSI as many studies have shown controversial and inconsistent results. Literature does not suggest PSI techniques as a gold standard in TKA, and therefore it cannot be recommended as a standard technique in standard, not complicated primary TKA. Moreover, literature does not underline any improvement in components alignment, surgical time, blood loss or functional outcomes. Nevertheless, many patients who underwent TKA suffered a previous trauma. In case of deformities, like femoral or tibial fractures healed with a malalignment, preoperative planning may result difficult, and some intra-operative technical difficulties can occur, such as the use of intra-medullar rod. In these selected cases, PSIs may be very useful to avoid errors in alignment and planning.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.