ArticleInternational journal of ophthalmology2016
Prevalence and risk factors of lens opacities in rural populations living at two different altitudes in China.
Article in International journal of ophthalmology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 5 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 5 syntheses or guidelines pooled it.
- Vitamin D and Ocular Diseases: A Systematic Review.International journal of molecular sciences · 2022Pooled it
- Correlation of Sunlight Exposure and Different Morphological Types of Age-Related Cataract.BioMed research international · 2021Pooled it
- Global and regional prevalence of age-related cataract: a comprehensive systematic review and meta-analysis.Eye (London, England) · 2020Pooled it
- Cataract frequency and subtypes involved in workers assessed for their solar radiation exposure: a systematic review.Acta ophthalmologica · 2018Pooled it
- Statin Use and the Risk of Cataracts: A Systematic Review and Meta-Analysis.Journal of the American Heart Association · 2017Pooled it
- Comparison of a swept-source optical coherence tomograph device (MT9000) to a partial coherence interferometry-based biometer (IOLMaster 500) in a high-altitude environment.Scientific reports · 2026Article
- Sex-specific associations of prenatal Chinese famine exposure with cataract risk at age sixty: a cross-sectional study.BMC women's health · 2024Article
- Progress in the Application of Microneedles in Eye Disorders and the Proposal of the Upgraded Microneedle with Spinule.Pharmaceutical research · 2024Review
- Article
- Mitotic Activation Around Wound Edges and Epithelialization Repair in UVB-Induced Capsular Cataracts.Investigative ophthalmology & visual science · 2021Article
- Solar Radiation Exposure and Outdoor Work: An Underestimated Occupational Risk.International journal of environmental research and public health · 2018Review
- Environmental effects of ozone depletion and its interactions with climate change: Progress report, 2016.Photochemical & photobiological sciences : Official journal of the European Photochemistry Association and the European Society for Photobiology · 2017Article
- Prevalence and associated factors of presbyopia among school teachers in Gondar city, Northwest Ethiopia, 2016.Clinical optometry · 2017Article
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Authors and funding
11 authors.
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Abstract
aimTo investigate the prevalence of and risk factors for lens opacities in populations living at two different altitudes in China.
methodsA total of 813 subjects aged ≥40y in Lhasa (Tibet Autonomous Region, China. Altitude: 3658 m) and Shaoxing (Zhejiang Province, China. Altitude: 15 m) were underwent eye examinations and interviewed in this cross-sectional study. Participants' lens opacities were graded according to the Lens Opacities Classification System II (LOCS II) and the types of opacities with LOCS II scores ≥2 were determined. Univariate and stepwise logistic regression were used to evaluate the associations of independent risk factors with lens opacities.
resultsLens opacities were significantly more prevalent in the high-altitude than in the low-altitude area (χ (2)=10.54, P<0.001). Lens opacities appear to develop earlier in people living at high than at low altitude. The main types of lens opacity in Lhasa and Shaoxing were mixed (23.81%) and cortical (17.87%), respectively. Independent risk factors associated with all lens opacities were age, ultraviolet (UV) radiation exposure, and educational level. Compared with participants aged 40-49y, the risk of lens opacities increased gradually from 2 to 85 times per 10y [odds ratio (OR)=2.168-84.731, P<0.05). The risk of lens opacities was about two times greater in participants with the highest UV exposure than in those with the lowest exposure (OR=2.606, P=0.001). Educational level was inversely associated with lens opacities; literacy deceased the risk by about 25% compared with illiteracy (OR=0.758, P=0.041).
conclusionOld age, higher UV exposure and lower educational level are important risk factors for the development of lens opacities. Lens opacities are more prevalent among high-altitude than low-altitude inhabitants.
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