Evidence map›Paper›PMID 27162671›Full record

ArticleJournal of thoracic disease2016

Evaluation of pulmonary nodules in Asian population.

Chee K Phua, Wen Y Sim, Kuan Sen Tee, Sennen J W Lew, Albert Y H Lim, Dessmon Y H Tai, Soon Keng Goh, Ai Ching Kor, Alan W K Ng, John Abisheganaden and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Chee K PhuaDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Wen Y SimDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Kuan Sen TeeDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Sennen J W LewDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Albert Y H LimDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Dessmon Y H TaiDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Soon Keng GohDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Ai Ching KorDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Alan W K NgDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
John AbisheganadenDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Akash VermaDepartment of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore 308433, Singapore.
Tan Tock Seng Hospital · SG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAmerican College of Chest Physicians (ACCP) provides guidelines to manage pulmonary nodules. Pulmonary nodules however can be malignant or benign. Similar incidence of tuberculosis (TB) and lung cancer in Asian countries raises concern over the relevance of suggested guidelines in Asian population. There is little data on the pattern of clinical practice in the management of pulmonary nodules in Asian country (Singapore). Our study describes the current pattern of clinical practice in this area highlighting the variation in practice and discussing the potential reasons.

methodsRetrospective review of the medical records of patients diagnosed with lung cancer in 2010.

resultsSixty nodules were identified in 32 patients. Nodules were detected incidentally on routine imaging in 7 (21.9%) patients. TB contact tracing and pre-employment screening were common ways by which nodules were detected incidentally. Over one third (37.5%) were non-smokers. Majority of nodules were located in the upper lobes of right and left lung followed by right lower lobe (RLL). Only few patients 8 (25%) had positron emission tomography (PET) scan for staging purposes. There were no difference in survival between patients who presented with single, 747 (range, 25-1,840) days vs. multiple nodules 928 (range, 30-2,572) days, P=0.26. In a retrospective analysis of malignancy risk with the probability calculator, 62.5% patients were at low-moderate risk whilst 32.5% were at high risk.

conclusionsThe clinical practice of managing pulmonary nodules in Asian population differs from ACCP guidelines. None of the patient had pre-test probability calculated, and few had PET scan. This is because upper lobe predominance of lung cancer is identical to TB, non-smoking history does not have any weight in discounting malignancy risk where many of the Asian lung cancer patients are non-smokers, and the local endemicity of TB and its confounding effect on radiological findings of CT scan and PET scan.

Indexed as

Asiacancer (lung)histoplasmosisNoduletuberculosis (TB)

Identifiers

PMID27162671
PMCPMC4842803
OpenAlexW2317443722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.