ArticleJournal of thoracic disease2016
Severe adenovirus community-acquired pneumonia in immunocompetent adults: chest radiographic and CT findings.
Article in Journal of thoracic disease, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 34 citations in OpenAlex.
- Adenovirus Infections in Hematologic Malignancy and Hematopoietic Cell Transplant Recipients: Epidemiology, Diagnosis, and Management.Infection & chemotherapy · 2026Review
- hMPV co-infections: Distinct immunopathogenic mechanisms and clinical implications of viral and bacterial pathogenesis.Folia microbiologica · 2025Review
- Clinical and Radiological Features of an Adenovirus Type 7 Outbreak in Split-Dalmatia County, Croatia, 2022-2023.Pathogens (Basel, Switzerland) · 2024Article
- Imaging of pulmonary infections encountered in the emergency department in post-COVID 19 era- common, rare and exotic. Bacterial and viral.Emergency radiology · 2024Review
- Construction of a bivalent vaccine candidate against HAdV4/HAdV7 based on capsid-display strategy via Red-homologous recombination and counter-selection methodology.Biosafety and health · 2024Article
- Human adenovirus infections in pediatric population - An update on clinico-pathologic correlation.Biomedical journal · 2022Review
- Clinical Features and Temporal Lung Radiographic Changes in 25 Patients Recovering from COVID-19 Pneumonia: A Retrospective Case-Control Study.Medical science monitor : international medical journal of experimental and clinical research · 2021Article
- Influence of the timing of bronchoscopic alveolar lavage on children with adenovirus pneumonia: a comparative study.BMC pulmonary medicine · 2021Observational
- Learning to learn by yourself: Unsupervised meta-learning with self-knowledge distillation for COVID-19 diagnosis from pneumonia cases.International journal of intelligent systems · 2021Article
- Radiological, epidemiological and clinical patterns of pulmonary viral infections.European journal of radiology · 2021Review
- Discovery of a Small Molecule Inhibitor of Human Adenovirus Capable of Preventing Escape from the Endosome.International journal of molecular sciences · 2021Article
- Prevalence and clinical impact of VIral Respiratory tract infections in patients hospitalized for Community-Acquired Pneumonia: the VIRCAP study.Internal and emergency medicine · 2020Observational
- Severe community acquired adenovirus pneumonia in an immunocompetent host successfully treated with IV Cidofovir.Respiratory medicine case reports · 2020Article
- NACHT, LRR, and PYD domains-containing Protein 3 and LL-37: prognostic value of new biomarkers in community-acquired pneumonia.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2019Article
- Spectrum of imaging findings in pulmonary infections. Part 1: Bacterial and viral.Polish journal of radiology · 2019Review
- The Repertoire of Adenovirus in Human Disease: The Innocuous to the Deadly.Biomedicines · 2018Review
- Severe Respiratory Viral Infections: New Evidence and Changing Paradigms.Infectious disease clinics of North America · 2017Review
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundSevere adenovirus pneumonia and its associated imaging features are well-described in immunocompromised patients but are rare and poorly understood in immunocompetent adults. We sought to describe the radiographic and CT findings of severe adenovirus community-acquired pneumonia (CAP) in eight immunocompetent adults.
methodsWe reviewed systematically chest imaging manifestations of laboratory-confirmed severe adenovirus pneumonia in eight immunocompetent adults from April 2012 to April 2014.
resultsAll patients showed abnormal results on initial chest radiograph and CT, with the exception of one normal initial chest radiograph. The abnormalities of the initial chest radiographs were unilateral (n=4) or bilateral (n=3), including consolidation (n=4), dense patchy opacity (n=3), ground glass opacity (GGO) (n=1), and pleural effusion (n=1). The initial CT findings consisted of unilateral (n=5) and bilateral (n=3) abnormalities, including consolidation (n=8), GGO (n=2), pleural effusion (n=3) and small nodules (n=1). Focal consolidation was the predominant finding in six patients whose initial CT scans were examined within one week after illness onset. Follow-up radiologic findings showed rapid development of bilateral consolidation within ten days after illness onset, usually accompanied by adjacent ground-glass opacity and pleural effusion. The parenchymal abnormalities began to absorb around two weeks after illness onset, with no appearances of fibrosis.
conclusionsSevere adenovirus CAP in immunocompetent adults mainly appears as focal consolidation followed by rapid progression to bilateral consolidation, usually accompanied by adjacent GGO and pleural effusion, which may resemble bacterial pneumonia. Adenovirus should be considered in severe pneumonia cases with negative cultures and failure to respond to antibiotics.
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