ReviewWorld journal of diabetes2016
Positive evidence for vitamin A role in prevention of type 1 diabetes.
Review in World journal of diabetes, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 20 citations in OpenAlex.
- Vitamin supplementation and its effect on incident type 1 diabetes mellitus and islet autoimmunity: a systematic review and meta-analysis.Frontiers in immunology · 2025Pooled it
- Article
- Association between vitamin A and D levels and the risk of type 1 diabetes mellitus in children.Frontiers in nutrition · 2026Article
- Vitamin A and Its Related Diseases.Food science & nutrition · 2025Review
- Evaluating Risk: Benefit Ratio of Fat-Soluble Vitamin Supplementation to SARS-CoV-2-Infected Autoimmune and Cancer Patients: Do Vitamin-Drug Interactions Exist?Life (Basel, Switzerland) · 2022Review
- β-Carotene: Preventive Role for Type 2 Diabetes Mellitus and Obesity: A Review.Molecules (Basel, Switzerland) · 2020Review
- Early Nutrition and Risk of Type 1 Diabetes: The Role of Gut Microbiota.Frontiers in nutrition · 2020Review
- [Protective effect of vitamin A on residual pancreatic β cell function in children with type 1 diabetes mellitus].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2018Article
- Ischemic colitis of the colon in streptozotocin-induced diabetic rats.Molecular and cellular biochemistry · 2018Article
- Effect of Natural Compounds on NK Cell Activation.Journal of immunology research · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Type 1 diabetes mellitus (T1DM) as one of the most well-known autoimmune disease, results from the destruction of β-cells in pancreas by autoimmune process. T1DM is fatal without insulin treatment. The expansion of alternative treatment to insulin is a dream to be fulfilled. Currently autoimmunity is considered as main factor in development of T1DM. So manipulation of the immune system can be considered as alternative treatment to insulin. For the past decades, vitamin A has been implicated as an essential dietary micronutrient in regulator of immune function. Despite major advantage in the knowledge of vitamin A biology, patients who present T1DM are at risk for deficiency in vitamin A and carotenoids. Applying such evidences, vitamin A treatment may be the key approach in preventing T1DM.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.