ArticleJournal of Cancer2016
Survival and Quality of Life Benefit after Endoscopic Management of Malignant Central Airway Obstruction.
Article in Journal of Cancer, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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Who cites it
32 citing papers in PubMed.
- Efficacy and safety of transbronchial microwave ablation therapy under moderate sedation in malignant central airway obstruction patients with respiratory failure: a single-institution retrospective study.Journal of cancer research and clinical oncology · 2021Trial
- International Consensus on Severe Lung Cancer-The Second Edition.Translational lung cancer research · 2026Review
- Outcomes and Prognostic Analysis of Therapeutic Bronchoscopy in Non-Small Cell Lung Cancer (NSCLC) Patients With Respiratory Failure Secondary to Malignant Central Airway Obstruction (MCAO).Pulmonary medicine · 2026Article
- Local methylprednisolone irrigation and tolerability after PTS-based bronchoscopic treatment for malignant central airway obstruction: a retrospective study.Frontiers in medicine · 2026Article
- Prognostic factors and clinical outcomes of stenting on malignant central airway obstruction.Scientific reports · 2025Article
- Silver-coated silicone stents as an approach to prevent bacterial colonization of central airways after tracheobronchial stenting.Frontiers in microbiology · 2025Article
- Successful stent removal after chemoradiotherapy followed by durvalumab for locally advanced non-small cell lung cancer with airway stenosis: A report of three cases.Respiratory medicine case reports · 2025Article
- Effectiveness of AERO Stent Placement for Malignant Airway Disorder in Patients with a Poor Performance Status.Internal medicine (Tokyo, Japan) · 2024Article
- Interventional bronchoscopy in lung cancer treatment.Breathe (Sheffield, England) · 2024Review
- The role of interventional bronchoscopy in the management of malignant central airway obstruction.Respiratory medicine case reports · 2024Article
- Early extracorporeal membrane oxygenation as bridge for central airway obstruction patients caused by neck and chest tumors to emergency surgery.Scientific reports · 2023Article
- Review of the clinical outcomes of therapeutic bronchoscopy for central airway obstruction.Mediastinum (Hong Kong, China) · 2023Review
- Gamma Irradiation Processing on 3D PCL Devices-A Preliminary Biocompatibility Assessment.International journal of molecular sciences · 2022Article
- Therapeutic bronchoscopy in malignant central airway obstruction: is technical success always clinically relevant?Journal of thoracic disease · 2022Article
- Central airway obstruction: is it time to move forward?BMC pulmonary medicine · 2022Article
- Predictors of survival and technical success of bronchoscopic interventions in malignant airway obstruction.Journal of thoracic disease · 2021Article
- Tracheobronchial stents in patients with malignant airway disease: Finnish tertiary care experience.Interactive cardiovascular and thoracic surgery · 2021Article
- Utility of bronchoscopic intra-tumoral alcohol injection to restore airway patency.Journal of thoracic disease · 2021Article
- Clinical effects of cisplatin plus recombinant human endostatin (rh-endostatin) intratumoral injection on malignant central airway obstruction: a retrospective analysis of 319 cases.Journal of thoracic disease · 2021Article
- Interventional bronchoscopy for HPV 16 and 66 with the use of spraying interferon-α (2b) plus bevacizumab and anti-reflux agent.Respiratory medicine case reports · 2021Article
Corrections and comments
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Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough interventional management of malignant central airway obstruction (mCAO) is well established, its impact on survival and quality of life (QoL) has not been extensively studied.
aimWe prospectively assessed survival, QoL and dyspnea (using validated EORTC questionnaire) in patients with mCAO 1 day before interventional bronchoscopy, 1 week after and every following month, in comparison to patients who declined this approach. Material/Patients/Methods: 36 patients underwent extensive interventional bronchoscopic management as indicated, whereas 12 declined. All patients received full chemotherapy and radiotherapy as indicated. Patients of the 2 groups were matched for age, comorbidities, type of malignancy and level of obstruction. Follow up time was 8.0±8.7 (range 1-38) months.
resultsMean survival for intervention and control group was 10±9 and 4±3 months respectively (p=0.04). QoL improved significantly in intervention group patients up to the 6(th) month (p<0.05) not deteriorating for those surviving up to 12 months. Dyspnea decreased in patients of the intervention group 1 month post procedure remaining reduced for survivors over the 12th month. Patients of the control group had worse QoL and dyspnea in all time points.
conclusionsInterventional management of patients with mCAO, may achieve prolonged survival with sustained significant improvement of QoL and dyspnea.
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