ArticleProceedings of SPIE--the International Society for Optical Engineering2016
3D registration of intravascular optical coherence tomography and cryo-image volumes for microscopic-resolution validation.
Article in Proceedings of SPIE--the International Society for Optical Engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
6 citing papers in PubMed.
- Mitochondria of T Lymphocytes Promote Anti-Pulmonary Tumor Immune Response.World journal of oncology · 2024Article
- Lethal effects of mitochondria via microfluidics.Bioengineering & translational medicine · 2023Article
- Shrimp miR-965 transfers tumoricidal mitochondria.Biological procedures online · 2022Article
- Co-registration of pre- and post-stent intravascular OCT images for validation of finite element model simulation of stent expansion.Proceedings of SPIE--the International Society for Optical Engineering · 2020Article
- Automated stent coverage analysis in intravascular OCT (IVOCT) image volumes using a support vector machine and mesh growing.Biomedical optics express · 2019Article
- Voxel-based plaque classification in coronary intravascular optical coherence tomography images using decision trees.Proceedings of SPIE--the International Society for Optical Engineering · 2018Article
Corrections and comments
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Authors and funding
14 authors.
Funding
Abstract
High resolution, 100 frames/sec intravascular optical coherence tomography (IVOCT) can distinguish plaque types, but further validation is needed, especially for automated plaque characterization. We developed experimental and 3D registration methods, to provide validation of IVOCT pullback volumes using microscopic, brightfield and fluorescent cryo-image volumes, with optional, exactly registered cryo-histology. The innovation was a method to match an IVOCT pull-back images, acquired in the catheter reference frame, to a true 3D cryo-image volume. Briefly, an 11-parameter, polynomial virtual catheter was initialized within the cryo-image volume, and perpendicular images were extracted, mimicking IVOCT image acquisition. Virtual catheter parameters were optimized to maximize cryo and IVOCT lumen overlap. Local minima were possible, but when we started within reasonable ranges, every one of 24 digital phantom cases converged to a good solution with a registration error of only +1.34±2.65μm (signed distance). Registration was applied to 10 ex-vivo cadaver coronary arteries (LADs), resulting in 10 registered cryo and IVOCT volumes yielding a total of 421 registered 2D-image pairs. Image overlays demonstrated high continuity between vascular and plaque features. Bland-Altman analysis comparing cryo and IVOCT lumen area, showed mean and standard deviation of differences as 0.01±0.43 mm
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Registered trials
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