Evidence map›Paper›PMID 27162191›Full record

ArticleThe journal of sexual medicine2016

Conservative Therapy is an Effective Option in Patients With Localized Infection After Penile Implant Surgery.

Mohamad Habous, Mohammed Farag, Ben Williamson, Osama Laban, Saad Mahmoud, Osama Abdelwahab, Mohamed Elkhouly, Usama Kamil, Saleh Binsaleh, Raanan Tal and 2 more

Open access · greenAbstract read
In one paragraph

Article in The journal of sexual medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.6field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
  4. Risky business: penile prosthesis in high-risk patients.Translational andrology and urology · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Surgical tips in difficult penile prosthetic surgery: a narrative review.International journal of impotence research · 2023
    Review
  9. Review
  10. Case - Conservative management of deep penile skin infection post-three-piece penile prosthesis implantation.Canadian Urological Association journal = Journal de l'Association des urologues du Canada · 2021
    Article
  11. Review
  12. Correlation of fasting blood sugar at the time of penile prosthesis surgery with the level of glycated hemoglobin and the outcome of surgery.African journal of urology : the official journal of the Pan African Urological Surgeons' Association (PAUSA) · 2021
    Article
  13. Penile Prosthesis Infection: Myths and Realities.The world journal of men's health · 2019
    Review
  14. Article
  15. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors at 9 institutions in 6 countries.

Mohamad HabousElaj Medical Centers, Urology and Andrology Department, Jedda, Saudi Arabia. Electronic address: drmhabos@hotmail.com.
Mohammed FaragAl-azhar University, Urology Department, Cairo, Egypt.
Ben WilliamsonUniversity Hospitals Birmingham, Birmingham, UK.
Osama LabanKing Khaled Hospital, Tabouk, Saudi Arabia.
Saad MahmoudElaj Medical Centers, Urology and Andrology Department, Jedda, Saudi Arabia.
Osama AbdelwahabBenha University, Urology Department, Benha, Egypt.
Mohamed ElkhoulyElaj Medical Centers, Urology and Andrology Department, Jedda, Saudi Arabia.
Usama KamilElaj Medical Centers, Urology and Andrology Department, Jedda, Saudi Arabia.
Saleh BinsalehDivision of Urology, Department of Surgery, Faculty of Medicine, King Saud University, Riyadh, Saudi Arabia.
Raanan TalMale Sexual Dysfunction & Male Infertility, Urology Department, Rambam Health Care Campus, Haifa, Israel.
David RalphSt Peters Andrology Centre &The Institute of Urology, UCLH, London, UK.
John P MulhallSexual & Reproductive Medicine Program, Memorial Sloan Kettering Cancer Center, New York, USA.
Jeddah University · SAAl-Azhar University · EGBenha University · EGKing Khaled Hospital · SAMemorial Sloan Kettering Cancer Center · USNIHR Surgical Reconstruction and Microbiology Research Centre · GBRambam Health Care Campus · ILRiyadh Armed Forces Hospital · SASt Peter's Hospital · GB

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI Nicholas D Socci · 1985 to 2026
$347.4M
NCI NIH HHS P30 CA008748
6 · The paper itself

Abstract

introductionTraditionally, penile implant (PI) infections have been managed by removal with immediate or delayed replacement. Recently, interest has been focused on conservative therapy (CT) using antibiotic therapy.

aimTo investigate the success rate and predictive factors affecting the outcome of CT in PI infection patients.

methodsPatients diagnosed with early, localized PI infection were considered candidates for CT. Exclusion criteria included temperature >37.5°C, WBC >13,000/μL, and appearance of any sign of sepsis. In patients with purulent drainage, culture swabs were taken and an antibiotic was chosen based on sensitivity results. Oral antibiotics were used until the local infection was completely resolved. Patients were evaluated weekly during this process.

resultsThirty-seven patients were retrospectively reviewed and constituted the study population. Mean age was 58.1 (range 37-85; SD 9.9) years. All were diabetic. Mean BMI was 31.8 (range 24-47; SD 5.0). PI was malleable in 33 cases and inflatable in 4 cases. Culture results (n = 19) included Staphylococcus epidermidis (42 %), pseudomonas (21%), Escherichia coli (21%), and S aureus (16%). Four of 37 patients needed the PI removed due to CT failure and onset of systemic symptoms, at a mean time-point of 75 ± 1.8 days after CT commencement. In men who were cured, mean time to complete healing was 49 (range 29-97; SD 15.8) days. Two of 37 patients (5%) had PI removal because of persistent penile pain despite complete wound healing, at a mean time point of 128 ± 2.5 days after CT commencement. All men managed conservatively resumed sexual intercourse.

conclusionCT of localized PI infection appears to be a viable option for such patients, with the majority of patients retaining their implant and resuming sexual activity.

Indexed as

AdultAgedAged, 80 and overAnti-Bacterial AgentsCoitusConservative TreatmentDevice RemovalHumansMaleMiddle AgedPenile ProsthesisProsthesis-Related InfectionsRetrospective StudiesAnti-Bacterial AgentsConservative TherapyImplantInfectionPenile ProsthesisSalvageSurgery

Identifiers

PMID27162191
PMCPMC5317031
OpenAlexW2379978873

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.