Evidence map›Paper›PMID 27161767›Full record

ArticleTrends in parasitology2016

Tuft Cells: A New Flavor in Innate Epithelial Immunity.

Richard K Grencis, John J Worthington

Abstract readComment
PubMed Publisher
In one paragraph

Article in Trends in parasitology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  14. c-KitScientific reports · 2018
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Richard K GrencisFaculty of Life Sciences, University of Manchester, Manchester, UK. Electronic address: richard.grencis@manchester.ac.uk.
John J WorthingtonFaculty of Health and Medicine, University of Lancaster, Lancaster, UK. Electronic address: j.j.worthington@lancaster.ac.uk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

How host cells sense intestinal parasitic infection and initiate the appropriate immune response has long been a focus of many immunologists. Three new papers now identify a critical role for tuft cells, an epithelial cell type involved in perception of taste, as key players that kick-start type 2 immunity.

Indexed as

AnimalsEpithelial CellsHumansImmunity, InnateParasitic DiseasesSignal Transduction

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.