Evidence map›Paper›PMID 27161022›Full record

ArticleUltrasonics2016

Adaptive windowing in contrast-enhanced intravascular ultrasound imaging.

Brooks D Lindsey, K Heath Martin, Xiaoning Jiang, Paul A Dayton

Abstract readEvaluation Study
PubMed Full text at PMC Publisher
In one paragraph

Article in Ultrasonics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Dual-Frequency Piezoelectric Endoscopic Transducer for Imaging Vascular Invasion in Pancreatic Cancer.IEEE transactions on ultrasonics, ferroelectrics, and frequency control · 2017
    Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Brooks D LindseyJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, CB7575 Chapel Hill, NC 27599, United States. Electronic address: brooks.lindsey@unc.edu.
K Heath MartinJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, CB7575 Chapel Hill, NC 27599, United States.
Xiaoning JiangDepartment of Mechanical and Aerospace Engineering, North Carolina State University, 911 Oval Drive, 3282 Engineering Building III, Campus Box 7910, North Carolina State University, Raleigh, NC, United States; Joint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, CB7575 Chapel Hill, NC 27599, United States.
Paul A DaytonJoint Department of Biomedical Engineering, University of North Carolina at Chapel Hill and North Carolina State University, CB7575 Chapel Hill, NC 27599, United States; Biomedical Research Imaging Center, University of North Carolina at Chapel Hill, Marsico Hall, Chapel Hill, NC 27599, United States.

Funding

Dual-frequency intravascular arrays for functional imaging of atherosclerosisR01EB015508 · NIBIB · NORTH CAROLINA STATE UNIVERSITY RALEIGH · PI JIANG, XIAONING · 2012 to 2015
$2.0M
Contrast-enhanced intravascular ultrasound imaging of vascular invasionF32EB018715 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI LINDSEY, BROOKS D · 2015 to 2016
$114k
NIBIB NIH HHS F32 EB018715NIBIB NIH HHS R01 EB015508
6 · The paper itself

Abstract

Intravascular ultrasound (IVUS) is one of the most commonly-used interventional imaging techniques and has seen recent innovations which attempt to characterize the risk posed by atherosclerotic plaques. One such development is the use of microbubble contrast agents to image vasa vasorum, fine vessels which supply oxygen and nutrients to the walls of coronary arteries and typically have diameters less than 200μm. The degree of vasa vasorum neovascularization within plaques is positively correlated with plaque vulnerability. Having recently presented a prototype dual-frequency transducer for contrast agent-specific intravascular imaging, here we describe signal processing approaches based on minimum variance (MV) beamforming and the phase coherence factor (PCF) for improving the spatial resolution and contrast-to-tissue ratio (CTR) in IVUS imaging. These approaches are examined through simulations, phantom studies, ex vivo studies in porcine arteries, and in vivo studies in chicken embryos. In phantom studies, PCF processing improved CTR by a mean of 4.2dB, while combined MV and PCF processing improved spatial resolution by 41.7%. Improvements of 2.2dB in CTR and 37.2% in resolution were observed in vivo. Applying these processing strategies can enhance image quality in conventional B-mode IVUS or in contrast-enhanced IVUS, where signal-to-noise ratio is relatively low and resolution is at a premium.

Indexed as

Contrast MediaAlgorithmsAnimalsAtherosclerosisChick EmbryoComputer SimulationData Interpretation, StatisticalImage EnhancementImage Interpretation, Computer-AssistedModels, StatisticalPhantoms, ImagingReproducibility of ResultsSensitivity and SpecificitySignal Processing, Computer-AssistedSwineUltrasonography, InterventionalContrast MediaAdaptive beamformingContrast-enhanced ultrasoundHigh frequency ultrasoundIntravascular ultrasoundPhase coherence factorSuperharmonic

Identifiers

PMID27161022
PMCPMC4899141

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.