ArticleBioMedicine2016
Prevalence and factors of elevated alanine aminotransferase in central Taiwan - a retrospective study.
Article in BioMedicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
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Who cites it
14 citing papers in PubMed, 17 citations in OpenAlex.
- Article
- Traditional Chinese medicine for heart failure with preserved ejection fraction: clinical evidence and potential mechanisms.Frontiers in pharmacology · 2023Review
- Is elevated ALT associated with lifestyle risk factors? A population-based survey.Journal of diabetes and metabolic disorders · 2022Article
- Hyperuricemia Is Associated with Significant Liver Fibrosis in Subjects with Nonalcoholic Fatty Liver Disease, but Not in Subjects without It.Journal of clinical medicine · 2022Article
- Factors associated with elevated alanine aminotransferase in employees of a German chemical company: results of a large cross-sectional study.BMC gastroenterology · 2021Article
- Weight loss might be an early clinical feature of undiagnosed human immunodeficiency virus infection in Taiwan.BioMedicine · 2018Article
- Population-based cohort study investigating the association between weight loss and pyogenic liver abscesses.BioMedicine · 2017Article
- Association of use of selective serotonin reuptake inhibitors with risk of acute pancreatitis: a case-control study in Taiwan.European journal of clinical pharmacology · 2017Article
- Population-based cohort study investigating the correlation of diabetes mellitus with pleural empyema in adults in Taiwan.Medicine · 2017Observational
- Fluvastatin use and risk of acute pancreatitis: a population-based case-control study in Taiwan.BioMedicine · 2017Article
- Correlation between proton pump inhibitors and risk of pyogenic liver abscess.European journal of clinical pharmacology · 2017Article
- Etodolac and the risk of acute pancreatitis.BioMedicine · 2017Article
- Increased Risk of Pulmonary Tuberculosis in Patients with Depression: A Cohort Study in Taiwan.Frontiers in psychiatry · 2017Article
- Correlation of Proton Pump Inhibitors with Pulmonary Tuberculosis: A Case-Control Study in Taiwan.Frontiers in pharmacology · 2017Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aims of this study were to assess the prevalence of elevated alanine aminotransferase (ALT) and explore its related factors in Central Taiwan.
methodsThe study employed a retrospective design. The study selected a sample of 5,550 subjects between the years 2000 to 2004. The indivduals undergoing health examinations in a medical center in Central Taiwan were enrolled as subjects for this research. The patients' demographics, smoking and drinking habits, laboratory findings, and abdominal ultrasound results were collected and analyzed. Correlations between variables were analyzed using SPSS/ PC Windows for frequency distribution, t-test, Chi-square test, and multivariate logistic regression.
resultsThere were 3103 men (55.9%) and 2447 women (44.1%). The mean age was 49.4 ± 12.3 years (age range of 20-87). The overall prevalence of elevated ALT was 17.1%, with a significant gender difference (23.2% in men vs. 9.4% in women, P < .0001). The multivariate logistic regression analysis showed that the factors significantly related to elevated ALT were central obesity, hypertriglyceridemia, and anti-HCV positive in men and women.
conclusionsCentral obesity, hypertriglyceridemia, and anti-HCV positive are factors predominantly related to elevated ALT in men and women.
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