Evidence map›Paper›PMID 27160672›Full record

ReviewAnnals of biomedical engineering2016

Methods for Generating Hydrogel Particles for Protein Delivery.

Allen L Liu, Andrés J García

Abstract readReview
In one paragraph

Review in Annals of biomedical engineering, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Hydrogel Microparticles for Bone Regeneration.Gels (Basel, Switzerland) · 2023
    Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Hydrogels in Spinal Cord Injury Repair: A Review.Frontiers in bioengineering and biotechnology · 2022
    Review
  11. Microfluidic Chip Device forLangmuir : the ACS journal of surfaces and colloids · 2021
    Article
  12. Article
  13. Review
  14. Review
  15. Review
  16. Review
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Allen L LiuBioengineering Program, Georgia Institute of Technology, Atlanta, GA, USA.
Andrés J GarcíaPetit Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 2310 IBB Building, 315 Ferst Drive, Atlanta, GA, 30332, USA. andres.garcia@me.gatech.edu.

Funding

Hydrogels for hMSC delivery & engraftmentR01AR062368 · NIAMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 2012 to 2022
$3.5M
Osseo-reparative, integrin-specific materialsR01AR062920 · NIAMS · GEORGIA INSTITUTE OF TECHNOLOGY · PI GARCIA, ANDRES J · 2012 to 2021
$3.2M
Graduate Training for Rationally Designed, Integrative Biomaterials - GT BioMATT32EB006343 · NIBIB · GEORGIA INSTITUTE OF TECHNOLOGY · PI TEMENOFF, JOHNNA S · 2008 to 2018
$2.2M
Immuno-vasculogenic hydrogels for islet engraftment and localized toleranceR21EB020107 · NIBIB · UNIVERSITY OF LOUISVILLE · PI GARCIA, ANDRES J, SHIRWAN, HAVAL · 2015 to 2016
$418k
NIAMS NIH HHS R01 AR062368NIAMS NIH HHS R01 AR062920NIBIB NIH HHS R21 EB020107NIBIB NIH HHS T32 EB006343
6 · The paper itself

Abstract

Proteins represent a major class of therapeutic molecules with vast potential for the treatment of acute and chronic diseases and regenerative medicine applications. Hydrogels have long been investigated for their potential in carrying and delivering proteins. As compared to bulk hydrogels, hydrogel microparticles (microgels) hold promise in improving aspects of delivery owing to their less traumatic route of entry into the body and improved versatility. This review discusses common methods of fabricating microgels, including emulsion polymerization, microfluidic techniques, and lithographic techniques. Microgels synthesized from both natural and synthetic polymers are discussed, as are a series of microgels fashioned from environment-responsive materials.

Indexed as

AnimalsDrug Delivery SystemsHumansHydrogelsImmobilized ProteinsHydrogelsImmobilized ProteinsGrowth factorHydrogelMicrogelMicroparticlePEGPNIPAMProtein delivery

Identifiers

PMID27160672
PMCPMC5100897

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.