Evidence map›Paper›PMID 27160587›Full record

Observational studyCritical care (London, England)2016

Nighttime is associated with decreased survival and resuscitation efforts for out-of-hospital cardiac arrests: a prospective observational study.

Yosuke Matsumura, Taka-Aki Nakada, Koichiro Shinozaki, Takashi Tagami, Tomohisa Nomura, Yoshio Tahara, Atsushi Sakurai, Naohiro Yonemoto, Ken Nagao, Arino Yaguchi and 2 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it, 63 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Observational
  4. Efficacy of prehospital amiodarone on survival in adult out-of-hospital cardiac arrest: a retrospective observational study.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2026
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  9. Latent class analysis for identification of sub-phenotypes predicting prognosis in hospitalized out-of-hospital cardiac arrest.Journal of critical care medicine (Universitatea de Medicina si Farmacie din Targu-Mures) · 2025
    Article
  10. Article
  11. Wearable devices for out-of-hospital cardiac arrest: A population survey on the willingness to adhere.Journal of the American College of Emergency Physicians open · 2024
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  19. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 7 institutions in 1 country.

Yosuke MatsumuraDepartment of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, 260-8677, Japan.
Taka-Aki NakadaDepartment of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, 260-8677, Japan. taka.nakada@nifty.com.
Koichiro ShinozakiDepartment of Emergency and Critical Care Medicine, Chiba University Graduate School of Medicine, 1-8-1 Inohana, Chuo-ku, Chiba City, Chiba, 260-8677, Japan.
Takashi TagamiDepartment of Emergency and Critical Care Medicine, Nippon Medical School Hospital, 1-1-5 Sendagi Bunkyo-ku, Tokyo, 113-0022, Japan.
Tomohisa NomuraDepartment of Emergency and Critical Care Medicine, Juntendo University Nerima Hospital, 3-1-10 Takanodai, Nerima-ku, Tokyo, 177-0033, Japan.
Yoshio TaharaNational Cerebral and Cardiovascular Center Hospital, 5-7-1 Fujishiro-dai, Suita, Osaka, 565-8565, Japan.
Atsushi SakuraiDivision of Emergency and Critical Care Medicine, Department of Acute Medicine, Nihon University School of Medicine, 30-1 Oyaguchikamicho, Itabashi-ku, Tokyo, 173-0032, Japan.
Naohiro YonemotoDepartment of Biostatistics, Kyoto University School of Public Health, Kyoto, 606-8501, Japan.
Ken NagaoNihon University Surugadai Hospital, 1-6 Kanda-Surugadai, Chiyoda-ku, Tokyo, 101-8309, Japan.
Arino YaguchiDepartment of Critical Care and Emergency Medicine, Tokyo Women's Medical University, 8-1 Kawadacho, Shinjuku-ku, Tokyo, 162-8666, Japan.
Naoto MorimuraDepartment of Emergency Medicine, Yokohama City University Medical Center, 4 -57 Urafunecho, Minami-ku, Yokohama City, Kanagawa, 232-0024, Japan.
SOS-KANTO 2012 study group
Chiba University · JPNihon University · JPYokohama City University Medical Center · JPKyoto University · JPNational Cerebral and Cardiovascular Center · JPNippon Medical School Hospital · JPSurugadai Nihon University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWhether temporal differences alter the clinical outcomes of patients with out-of-hospital cardiac arrest (OHCA) remains inconclusive. Furthermore, the relationship between time of day and resuscitation efforts is unknown.

methodsWe studied adult OHCA patients in the Survey of Survivors after Out-of-Hospital Cardiac Arrest in the Kanto Region (SOS-KANTO) 2012 study from January 2012 to March 2013 in Japan. The primary variable was 1-month survival. The secondary outcome variables were prehospital and in-hospital resuscitation efforts by bystanders, emergency medical services personnel, and in-hospital healthcare providers. Daytime was defined as 0701 to 1500 h, evening was defined as 1501 to 2300 h, and night was defined as 2301 to 0700 h.

resultsDuring the study period, 13,780 patients were included in the analysis. The patients with night OHCA had significantly lower 1-month survival compared to the patients with daytime OHCA (night vs. daytime, adjusted odds ratio (OR) 1.66; 95 % confidence interval (CI), 1.34-2.07; P < 0.0001). The nighttime OHCA patients had significantly shorter call-response intervals, bystander CPR, in-hospital intubation, and in-hospital blood gas analyses compared to the daytime and evening OHCA patients (call-response interval: OR 0.95 and 95 % CI 0.93-0.96; bystander CPR: OR 0.85 and 95 % CI 0.78-0.93; in-hospital intubation: OR 0.85 and 95 % CI 0.74-0.97; and in-hospital blood gas analysis: OR 0.86 and 95 % CI 0.75-0.98).

conclusionsThere was a significant temporal difference in 1-month survival after OHCA. The nighttime OHCA patients had significantly decreased resuscitation efforts by bystanders and in-hospital healthcare providers compared to those with evening and daytime OHCA.

Indexed as

Survival AnalysisTime FactorsAgedAged, 80 and overCardiopulmonary ResuscitationFemaleHumansJapanMaleMiddle AgedOut-of-Hospital Cardiac ArrestProspective StudiesSurveys and QuestionnairesCardiopulmonary resuscitationCircadian rhythmHeart arrestOut-of-hospital cardiac arrestResuscitation

Identifiers

PMID27160587
PMCPMC4862118
OpenAlexW2345600460

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.