Evidence map›Paper›PMID 27160421›Full record

ArticleOrganic letters2016

Palladium-Catalyzed Selective α-Alkenylation of Pyridylmethyl Ethers with Vinyl Bromides.

Xiaodong Yang, Byeong-Seon Kim, Minyan Li, Patrick J Walsh

Abstract read
In one paragraph

Article in Organic letters, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
  2. Palladium-catalyzed benzylic C(spChemical science · 2021
    Article
  3. Article
  4. Review
  5. Alkenylation of C(spAngewandte Chemie (International ed. in English) · 2018
    Article
  6. Palladium-Catalyzed Triarylation of spAdvanced synthesis & catalysis · 2018
    Article
  7. Article
  8. Transition-Metal-Free Radical C(spJournal of the American Chemical Society · 2017
    Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Xiaodong YangKey Laboratory of Medicinal Chemistry for Natural Resource, Ministry of Education, School of Chemical Science and Technology, Yunnan University , Kunming, 650091, P. R. China.
Byeong-Seon KimRoy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
Minyan LiRoy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.
Patrick J WalshRoy and Diana Vagelos Laboratories, Department of Chemistry, University of Pennsylvania , 231 South 34th Street, Philadelphia, Pennsylvania 19104-6323, United States.

Funding

Arylation of weakly acidic sp3 hybridized C-H'sR01GM104349 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI WALSH, PATRICK J · 2013 to 2016
$1.3M
NIGMS NIH HHS R01 GM104349
6 · The paper itself

Abstract

An efficient palladium-catalyzed α-alkenylation of pyridylmethyl ethers with vinyl bromides is presented. A Pd/NIXANTPHOS-based catalyst system enables a mild and chemoselective coupling between a variety of pyridylmethyl ethers and vinyl bromides in good to excellent yields. Under the mild conditions, β,γ-unsaturated products are obtained without isomerization or Heck byproducts observed.

Indexed as

CatalysisChemistry Techniques, SyntheticEthersHydrogen BondingPalladiumPyridinesVinyl CompoundsEthersPalladiumPyridinesvinyl bromideVinyl Compounds

Identifiers

PMID27160421
PMCPMC4887130

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.