Evidence map›Paper›PMID 27160404›Full record

ArticleJournal of the American Society of Nephrology : JASN2016

Association between Preoperative Vascular Function and Postoperative Arteriovenous Fistula Development.

Michael Allon, Tom Greene, Laura M Dember, Joseph A Vita, Alfred K Cheung, Naomi M Hamburg, Peter B Imrey, James S Kaufman, Michelle L Robbin, Yan-Ting Shiu and 4 more

Abstract read
In one paragraph

Article in Journal of the American Society of Nephrology : JASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
15.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it, 76 citations in OpenAlex.

  1. Systematic review and meta-analysis of preoperative interventions to support the maturation of arteriovenous fistulae in patients with advanced kidney disease.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2023
    Pooled it
  2. Optimizing Dialysis Vascular Access: Moving beyond Fistula First.Clinical journal of the American Society of Nephrology : CJASN · 2026
    Review
  3. Human Data First: New Biological Premises for Arteriovenous Fistula Research.Arteriosclerosis, thrombosis, and vascular biology · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 7 institutions in 1 country.

Michael AllonDivision of Nephrology and mdallon@uab.edu.
Tom GreeneDivision of Nephrology, University of Utah, Salt Lake City, Utah.
Laura M DemberDivision of Nephrology, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania.
Joseph A VitaDivision of Cardiology, Boston University School of Medicine, Boston, Massachusetts.
Alfred K CheungDivision of Nephrology, University of Utah, Salt Lake City, Utah.
Naomi M HamburgDivision of Cardiology, Boston University School of Medicine, Boston, Massachusetts.
Peter B ImreyDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, Ohio; and.
James S KaufmanDivision of Nephrology, Veterans Affairs New York Healthcare System and New York University School of Medicine, New York.
Michelle L RobbinDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama.
Yan-Ting ShiuDivision of Nephrology, University of Utah, Salt Lake City, Utah.
Christi M TerryDivision of Nephrology, University of Utah, Salt Lake City, Utah.
Heidi R UmphreyDepartment of Radiology, University of Alabama at Birmingham, Birmingham, Alabama.
Harold I FeldmanDivision of Nephrology, Perelman School of Medicine of the University of Pennsylvania, Philadelphia, Pennsylvania.
Hemodialysis Fistula Maturation Study Group
University of Utah · USBoston University · USPediatric Nephrology of Alabama · USUniversity of Pennsylvania · USCleveland Clinic · USNew York University · USUniversity of Alabama at Birmingham · US

Funding

Frequent Hemodialysis Network Data Coordinating CenterU01DK066597 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI BECK, GERALD J · 2003 to 2010
$8.9M
Hemodialysis Fistula Maturation Consortium Data Coordinating CenterU01DK082236 · NIDDK · CLEVELAND CLINIC LERNER COM-CWRU · PI BECK, GERALD J · 2008 to 2013
$7.6M
Vascular Structure and Function in Arteriovenous Fistula MaturationU01DK082179 · NIDDK · UNIVERSITY OF WASHINGTON · PI HIMMELFARB, JONATHAN · 2008 to 2012
$2.5M
Determinants of Hemodialysis AV Fistula MaturationU01DK082232 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI DEMBER, LAURA M · 2008 to 2012
$2.4M
Modulation of the Hemodynamic Factors Associated with AVF MaturationU01DK082189 · NIDDK · UNIVERSITY OF FLORIDA · PI HUBER, THOMAS S · 2008 to 2012
$1.8M
Anatomic and functional predictors of arteriovenous fistula maturationU01DK082240 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI VAZQUEZ, MIGUEL A · 2008 to 2012
$1.8M
Maturation of Hemodialysis Arteriovenous FistulasU01DK082222 · NIDDK · UNIVERSITY OF UTAH · PI CHEUNG, ALFRED K · 2008 to 2012
$1.8M
Clinical, Hemodynamic and Biological Markers of AV Fistula MaturationU01DK082218 · NIDDK · UNIVERSITY OF CINCINNATI · PI ROY-CHAUDHURY, PRABIR · 2008 to 2012
$1.7M
NIDDK NIH HHS U01 DK066597NIDDK NIH HHS U01 DK082179NIDDK NIH HHS U01 DK082189NIDDK NIH HHS U01 DK082218NIDDK NIH HHS U01 DK082222NIDDK NIH HHS U01 DK082232NIDDK NIH HHS U01 DK082236NIDDK NIH HHS U01 DK082240
6 · The paper itself

Abstract

Arteriovenous fistula (AVF) maturation failure is the primary cause of dialysis vascular access dysfunction. To evaluate whether preoperative vascular functional properties predict postoperative AVF measurements, patients enrolled in the Hemodialysis Fistula Maturation Study underwent up to five preoperative vascular function tests (VFTs): flow-mediated dilation (FMD), nitroglycerin-mediated dilation (NMD), carotid-femoral pulse wave velocity, carotid-radial pulse wave velocity, and venous occlusion plethysmography. We used mixed effects multiple regression analyses to relate each preoperative VFT to ultrasound measurements of AVF blood flow rate and venous diameter at 1 day, 2 weeks, and 6 weeks after AVF placement. After controlling for AVF location, preoperative ultrasound measurements, and demographic factors (age, sex, race, and dialysis status), greater NMD associated with greater 6-week AVF blood flow rate and AVF diameter (per absolute 10% difference in NMD: change in blood flow rate =14.0%; 95% confidence interval [95% CI], 3.7% to 25.3%; P<0.01; change in diameter =0.45 mm; 95% CI, 0.25 to 0.65 mm; P<0.001). Greater FMD also associated with greater increases in 6-week AVF blood flow rate and AVF diameter (per absolute 10% difference in FMD: change in blood flow rate =11.6%; 95% CI, 0.6% to 23.9%; P=0.04; change in diameter =0.31 mm; 95% CI, 0.05 to 0.57 mm; P=0.02). None of the remaining VFT parameters exhibited consistent statistically significant relationships with both postoperative AVF blood flow rate and diameter. In conclusion, preoperative NMD and FMD positively associated with changes in 6-week AVF blood flow rate and diameter, suggesting that native functional arterial properties affect AVF development.

Indexed as

Arteriovenous Shunt, SurgicalAdultAgedBlood VesselsFemaleHumansMaleMiddle AgedPreoperative PeriodTreatment Outcomearteriovenous accessarteriovenous fistulavascular access

Identifiers

PMID27160404
PMCPMC5118472
OpenAlexW2346538021

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.