Evidence map›Paper›PMID 27160298›Full record

ArticleJournal of clinical hypertension (Greenwich, Conn.)2016

Do Combined Electrocardiographic and Echocardiographic Markers of Left Ventricular Hypertrophy Improve Cardiovascular Risk Estimation?

Cesare Cuspidi, Rita Facchetti, Carla Sala, Michele Bombelli, Marijana Tadic, Guido Grassi, Giuseppe Mancia

Open access · greenAbstract read
In one paragraph

Article in Journal of clinical hypertension (Greenwich, Conn.), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.2field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Cesare CuspidiDepartment of Health Science, University of Milano-Bicocca, Milano, Italy. cesare.cuspidi@unimib.it.
Rita FacchettiDepartment of Health Science, University of Milano-Bicocca, Milano, Italy.
Carla SalaDepartment of Clinical Sciences and Community Health, University of Milano and Fondazione Ospedale Maggiore Policlinico, Milano, Italy.
Michele BombelliDepartment of Health Science, University of Milano-Bicocca, Milano, Italy.
Marijana TadicUniversity Clinical Hospital Centre "Dragisa Misovic", Belgrade, Serbia.
Guido GrassiDepartment of Health Science, University of Milano-Bicocca, Milano, Italy.
Giuseppe ManciaDepartment of Health Science, University of Milano-Bicocca, Milano, Italy.
University of Milano-Bicocca · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · ITIstituti di Ricovero e Cura a Carattere Scientifico · ITUniversity Hospital Center Dr Dragiša Mišović · RS

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The authors estimated the risk of cardiovascular mortality associated with echocardiographic (ECHO) left ventricular hypertrophy (LVH) and subtypes of this phenotype in patients with and without electrocardiographic (ECG) LVH. A total of 1691 representatives of the general population were included in the analysis. During a follow-up of 211 months, 89 cardiovascular deaths were recorded. Compared with individuals with neither ECHO LVH nor ECG LVH, fully adjusted risk of cardiovascular mortality increased (hazard ratio [HR], 3.36; 95% confidence interval [CI], 1.51-7.47; P=.003) in patients with both ECHO-LVH and ECG-LVH, whereas the risk entailed by ECHO-LVH alone was of borderline statistical significance (P=.04). Combined concentric nondilated LVH and ECG-LVH, but not concentric nondilated LVH alone, predicted cardiovascular death (HR, 3.79; 95% CI, 1.25-11.38; P=.01). Similar findings were observed for eccentric nondilated LVH (HR, 3.37; 95% CI, 1.05-10.78; P=.04.). The present analysis underlines the value of combining ECG and ECHO in the assessment of cardiovascular prognosis related to abnormal left ventricular geometric patterns.

Indexed as

AdultAgedCardiovascular DiseasesEchocardiographyElectrocardiographyFemaleHumansHypertrophy, Left VentricularMaleMiddle AgedProportional Hazards ModelsRisk Factors

Identifiers

PMID27160298
PMCPMC8032070
OpenAlexW2377762917

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.