Evidence map›Paper›PMID 27160193›Full record

ArticleParasites & vectors2016

First report of Cytauxzoon sp. infection in a domestic cat from Portugal.

Ana Margarida Alho, Joana Silva, Maria João Fonseca, Filipa Santos, Cláudia Nunes, Luís Madeira de Carvalho, Manuel Rodrigues, Luís Cardoso

Open access · goldAbstract readCase Reports
In one paragraph

Article in Parasites & vectors, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
4.0field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 39 citations in OpenAlex.

  1. First Detection ofMicroorganisms · 2025
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  2. Diversity ofPathogens (Basel, Switzerland) · 2025
    Article
  3. Screening of Domestic Cats from North-Eastern Hungary forPathogens (Basel, Switzerland) · 2023
    Article
  4. Article
  5. Can Domestic Cats Act as Reservoirs ofPathogens (Basel, Switzerland) · 2023
    Article
  6. Molecular survey ofFrontiers in veterinary science · 2023
    Article
  7. Review
  8. The First Case ofAnimals : an open access journal from MDPI · 2022
    Article
  9. Veterinary sciences · 2022
    Article
  10. Article
  11. Article
  12. Pathogens (Basel, Switzerland) · 2021
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Ana Margarida AlhoCIISA, Faculty of Veterinary Medicine, Universidade de Lisboa (ULisboa), Lisbon, Portugal.
Joana SilvaBiopremier S.A., Campus da Faculdade de Ciências, ULisboa, Lisbon, Portugal.
Maria João FonsecaHospital do Gato, Lisbon, Portugal.
Filipa SantosHospital do Gato, Lisbon, Portugal.
Cláudia NunesBiopremier S.A., Campus da Faculdade de Ciências, ULisboa, Lisbon, Portugal.
Luís Madeira de CarvalhoCIISA, Faculty of Veterinary Medicine, Universidade de Lisboa (ULisboa), Lisbon, Portugal.
Manuel RodriguesBiopremier S.A., Campus da Faculdade de Ciências, ULisboa, Lisbon, Portugal.
Luís CardosoDepartment of Veterinary Sciences, School of Agrarian and Veterinary Sciences, University of Trás-os-Montes e Alto Douro (UTAD), Vila Real, Portugal. lcardoso@utad.pt.
University of Lisbon · PTUniversity of Trás-os-Montes and Alto Douro · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCytauxzoonosis is an emerging and life-threatening tick-borne feline disease caused by haemoprotozoan parasites of the genus Cytauxzoon. Information regarding epidemiological and clinical presentation of infections by species other than Cytauxzoon felis is scant. A case of Cytauxzoon sp. infection is described in a 2-year-old mixed breed male domestic cat from Portugal, presenting a history of acute lethargy, anorexia and pyrexia.

resultsComplete blood count revealed a severe anaemia, leucocytosis and thrombocytopenia. A pleural effusion was noticed on thoracic radiograph, and marked splenomegaly and free abdominal fluid were visualized by ultrasound. A molecular screening for the detection of causative agents of infectious anaemia was performed, and a positive result for Piroplasmorida was obtained. DNA sequencing of a 743 bp amplicon of the 18S rRNA gene (GenBank accession no. KU710344) revealed 99.9 % identity with Cytauxzoon manul.

conclusionsThis is the first report of Cytauxzoon sp. (clustering together with C. manul) in a felid from Portugal. Clinical manifestations along with molecular analysis suggest the hypothesis that domestic cats might be infected with and serve as a reservoir host for C. manul.

Indexed as

Acute DiseaseAnimalsAnorexiaBase SequenceCat DiseasesCatsDNA, ProtozoanDNA, RibosomalFeverLethargyMalePhylogenyPiroplasmidaPortugalProtozoan Infections, AnimalSequence Analysis, DNADNA, ProtozoanDNA, RibosomalCytauxzoon manulCytauxzoon sp.Domestic catHaemoparasitePiroplasmPortugalTick-borne disease

Identifiers

PMID27160193
PMCPMC4862187
OpenAlexW2336365036

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.