ArticleJournal of veterinary internal medicine2016
Whole-Body Barometric Plethysmography Characterizes Upper Airway Obstruction in 3 Brachycephalic Breeds of Dogs.
Article in Journal of veterinary internal medicine, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 53 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
53 citing papers in PubMed, 122 citations in OpenAlex.
- Vertebral Vascular Canal Dysplasia in Three Brachycephalic Breeds and Its Relationship With BOAS Grade.Veterinary radiology & ultrasound : the official journal of the American College of Veterinary Radiology and the International Veterinary Radiology Association · 2026Article
- Association of brachycephaly, sleep-disordered breathing, and inflammatory response in dogs.Journal of veterinary internal medicine · 2026Review
- One Health Insights into Pulmonary Hypertension: Bridging Human and Canine Medicine.Veterinary sciences · 2026Review
- 24-hour holter electrocardiography in the evaluation of French Bulldogs before and after rhinoplasty and staphylectomy procedures for correction of anatomical abnormalities of brachycephalic syndrome.Veterinary research communications · 2026Article
- Comparison of short- and long-term objective respiratory outcomes after surgery for brachycephalic obstructive airway syndrome.Veterinary surgery : VS · 2026Article
- Quantitative genetic analysis of respiratory function and related traits in Bulldogs, French Bulldogs and Pugs.PloS one · 2026Article
- Barometric whole-body plethysmography investigating breed-specific variations in dogs.Frontiers in veterinary science · 2026Article
- Timing-controlled concept for extubation in brachycephalic dogs: α2-bridged on-demand extubation.Frontiers in veterinary science · 2026Review
- A cross-sectional study into the prevalence and conformational risk factors of BOAS across fourteen brachycephalic dog breeds.PloS one · 2026Article
- A solution right under our nose? Crossbreeding extreme brachycephalic dogs results in better health outcomes while preserving behavioural profiles and dog-owner relationship quality.Animal welfare (South Mimms, England) · 2026Article
- Use of ultrasound to estimate tracheal diameter in unclipped brachycephalic dogs: A pilot study.Veterinary record open · 2025Article
- What Drives Pet Food Choices? A Systematic Literature Review.Animals : an open access journal from MDPI · 2025Review
- Evaluating the impact of a standardised pre-operative patient management protocol on major post-operative complications in dogs undergoing BOAS surgery.The Journal of small animal practice · 2025Article
- Complication rate and outcomes of laryngeal cuneiformectomy in dogs with advanced laryngeal collapse.Veterinary surgery : VS · 2025Article
- Comparison of remote and in-person respiratory function grading of brachycephalic dogs.Veterinary surgery : VS · 2025Article
- Bulldogs stenosis degree classification using synthetic images created by generative artificial intelligence.Scientific reports · 2025Article
- Demography and Causes of Mortality of Pugs Under Primary Veterinary Care in Australia.Veterinary sciences · 2025Article
- Short-term effects of brachycephalic obstructive airway syndrome surgery on fitness and exercise in brachycephalic dogs.Frontiers in veterinary science · 2025Article
- Abnormal shape of the pterygoid bone in French bulldogs: Prevalence and implication for cross-sectional area.The Canadian veterinary journal = La revue veterinaire canadienne · 2024Article
- Fur Cortisol in French Bulldogs with Different Manifestations of Brachycephalic Obstructive Airway Syndrome.Animals : an open access journal from MDPI · 2024Article
Corrections and comments
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Authors and funding
5 authors at 2 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundA novel test using whole-body barometric plethysmography (WBBP) was developed recently to diagnose brachycephalic obstructive airway syndrome (BOAS) in unsedated French bulldogs. HYPOTHESIS/
objectivesThe hypotheses of this study were: (1) respiratory characteristics are different between healthy nonbrachycephalic dogs and brachycephalic dogs; and among pugs, French bulldogs, and bulldogs; and (2) obesity and stenotic nares are risk factors for BOAS. The main objective was to establish a diagnostic test for BOAS in these 3 breeds. ANIMALS: A total of 266 brachycephalic dogs (100 pugs, 100 French bulldogs, and 66 bulldogs) and 28 nonbrachycephalic dogs.
methodsProspective study. Exercise tolerance tests with respiratory functional grading, and WBBP were performed on all dogs. Data from WBBP were associated with functional grades to train quadratic discriminant analysis tools to assign dogs to BOAS+ and BOAS- groups. A BOAS index (0-100%) was calculated for each dog. Receiver operating characteristic (ROC) curves were used to evaluate classification ability.
resultsMinute volume was decreased significantly in asymptomatic pugs (P = .009), French bulldogs (P = .026), and bulldogs (P < .0001) when compared to nonbrachycephalic controls. Respiratory characteristics were different among breeds and affected dogs had a significant increase in trace variation. The BOAS index predicted BOAS status for each breed with 94-97% (95% confidence interval [CI], 88.9-100%) accuracy (area under the ROC curve). Both obesity (P = .04) and stenotic nares (P = .004) were significantly associated with BOAS. CONCLUSIONS AND CLINICAL IMPORTANCE: The WBBP can be used as a clinical tool to diagnose BOAS noninvasively and objectively.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.