Evidence map›Paper›PMID 27159847›Full record

ArticleJournal of magnetic resonance imaging : JMRI2016

Fetal lung apparent diffusion coefficient measurement using diffusion-weighted MRI at 3 Tesla: Correlation with gestational age.

Onur Afacan, Ali Gholipour, Robert V Mulkern, Carol E Barnewolt, Judy A Estroff, Susan A Connolly, Richard B Parad, Sigrid Bairdain, Simon K Warfield

Abstract read
In one paragraph

Article in Journal of magnetic resonance imaging : JMRI, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Observational
  5. Review
  6. Observational
  7. Article
  8. Fetal MRI at 3 T: Principles to Optimize Success.Radiographics : a review publication of the Radiological Society of North America, Inc · 2023
    Article
  9. Article
  10. Assessment of the fetal lungs in utero.American journal of obstetrics & gynecology MFM · 2022
    Review
  11. Simultaneous Motion and Distortion Correction Using Dual-Echo Diffusion-Weighted MRI.Journal of neuroimaging : official journal of the American Society of Neuroimaging · 2020
    Article
  12. Fetal Echoplanar Imaging: Promises and Challenges.Topics in magnetic resonance imaging : TMRI · 2019
    Review
  13. Highlights on MRI of the fetal body.La Radiologia medica · 2018
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Onur AfacanDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Ali GholipourDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Robert V MulkernDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Carol E BarnewoltDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Judy A EstroffDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Susan A ConnollyDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.
Richard B ParadAdvanced Fetal Care Center, Boston Children's Hospital, Boston, Massachusetts, USA.
Sigrid BairdainHarvard Medical School, Boston, Massachusetts, USA.
Simon K WarfieldDepartment of Radiology, Boston Children's Hospital, Boston, Massachusetts, USA.

Funding

Improved Motion Robust MRI of ChildrenR01EB019483 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2015 to 2024
$3.9M
MRI Biomarkers of Patients with Tuberous Sclerosis Complex and AutismR01NS079788 · NINDS · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2013 to 2017
$3.6M
Prospective/Retrospective Motion Correction System for Motion Robust Pediatric MRIR44MH086984 · NIMH · ROBIN MEDICAL, INC. · PI NEVO, EREZ, WARFIELD, SIMON K · 2016 to 2018
$2.4M
Prospective/Retrospective Motion Correction System for Motion Robust Pediatric MRR42MH086984 · NIMH · ROBIN MEDICAL, INC. · PI NEVO, EREZ, WARFIELD, SIMON K · 2012 to 2014
$1.8M
Motion-robust super-resolution diffusion weighted MRI of early brain developmentR01EB018988 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI GHOLIPOUR-BABOLI, ALI · 2014 to 2017
$1.6M
Improved Quantitative Assessment of the Fetal Brain from 3D Volumetric MRIR01EB013248 · NIBIB · BOSTON CHILDREN'S HOSPITAL · PI WARFIELD, SIMON K · 2012 to 2015
$1.5M
NIBIB NIH HHS R01 EB013248NIBIB NIH HHS R01 EB018988NIBIB NIH HHS R01 EB019483NIMH NIH HHS R42 MH086984NIMH NIH HHS R44 MH086984NINDS NIH HHS R01 NS079788
6 · The paper itself

Abstract

purposeTo evaluate the feasibility of using diffusion-weighted magnetic resonance imaging (DW-MRI) to assess the fetal lung apparent diffusion coefficient (ADC) at 3 Tesla (T). MATERIALS AND

methodsSeventy-one pregnant women (32 second trimester, 39 third trimester) were scanned with a twice-refocused Echo-planar diffusion-weighted imaging sequence with 6 different b-values in 3 orthogonal diffusion orientations at 3T. After each scan, a region-of-interest (ROI) mask was drawn to select a region in the fetal lung and an automated robust maximum likelihood estimation algorithm was used to compute the ADC parameter. The amount of motion in each scan was visually rated.

resultsWhen scans with unacceptable levels of motion were eliminated, the lung ADC values showed a strong association with gestational age (P < 0.01), increasing dramatically between 16 and 27 weeks and then achieving a plateau around 27 weeks.

conclusionWe show that to get reliable estimates of ADC values of fetal lungs, a multiple b-value acquisition, where motion is either corrected or considered, can be performed. J. Magn. Reson. Imaging 2016;44:1650-1655.

Indexed as

Gestational AgeAgingDiffusionDiffusion Tensor ImagingFeasibility StudiesFemaleHumansImage EnhancementImage Interpretation, Computer-AssistedLungMalePrenatal DiagnosisReproducibility of ResultsSensitivity and SpecificityStatistics as TopicADCdiffusion MRIfetal lungfetal MRIgestational agemotion artifacts

Identifiers

PMID27159847
PMCPMC5436687

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.