Trial reportObstetrics and gynecology2016
Quality of Life and Sexual Function 2 Years After Vaginal Surgery for Prolapse.
Trial report in Obstetrics and gynecology, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to trial NCT00597935 (Operations and Pelvic Muscle Training in the Management of Apical Support Loss), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Operations and Pelvic Muscle Training in the Management of Apical Support Loss: The OPTIMAL Trial: A Randomized Trial of Sacrospinous Ligament Fixation (SSLF) Versus Uterosacral Ligament Suspension (ULS) With and Without Perioperative Behavioral Therapy/Pelvic Muscle Training
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Patient-reported outcome measures which assess body image in urogynaecology patients: a systematic review.International urogynecology journal · 2019Pooled it
- Improved body image after uterovaginal prolapse surgery with or without hysterectomy.International urogynecology journal · 2022Trial
- Sexual activity and function in women with advanced stages of pelvic organ prolapse, before and after laparoscopic or vaginal mesh surgery.International urogynecology journal · 2021Trial
- Recruitment and retention: A randomized controlled trial of video-enhanced versus standard consent processes within the E-OPTIMAL study.Clinical trials (London, England) · 2019Trial
- Trial
- Perioperative Behavioral Therapy and Pelvic Muscle Strengthening Do Not Enhance Quality of Life After Pelvic Surgery: Secondary Report of a Randomized Controlled Trial.Physical therapy · 2017Trial
- Sexual function after Anchorsure repair of sacrospinous ligament suspension in patients with pelvic organ prolapse: a prospective multicenter study.Scientific reports · 2026Observational
- Strategies to improve sexual health in women with urinary incontinence: A scoping review.PloS one · 2026Article
- Changes in sexual function over 12 months after native-tissue vaginal pelvic organ prolapse surgery with and without hysterectomy.Sexual medicine · 2023Article
- Patient's preference for sacrospinous hysteropexy or modified Manchester operation: A discrete choice experiment.BJOG : an international journal of obstetrics and gynaecology · 2023Article
- The PSR13, a tool for evaluating patient-perceived recovery after vaginal prolapse repair surgery.International urogynecology journal · 2022Article
- Article
- International Urogynecology Consultation Chapter 1 Committee 5: relationship of pelvic organ prolapse to associated pelvic floor dysfunction symptoms: lower urinary tract, bowel, sexual dysfunction and abdominopelvic pain.International urogynecology journal · 2021Article
- Impact of surgery on quality of life of Ugandan women with symptomatic pelvic organ prolapse: a prospective cohort study.BMC women's health · 2021Article
- Generic Health-Related Quality of Life in Patients Seeking Care for Pelvic Organ Prolapse.Female pelvic medicine & reconstructive surgery · 2021Article
- Risk Factors for Surgical Failure and Worsening Pelvic Floor Symptoms Within 5 Years After Vaginal Prolapse Repair.Obstetrics and gynecology · 2020Article
- Sexual Activity and Dyspareunia 1 Year After Surgical Repair of Pelvic Organ Prolapse.Obstetrics and gynecology · 2020Article
- Pelvic organ prolapse and sexual function.Nature reviews. Urology · 2020Review
- Mode of anesthesia and major perioperative outcomes associated with vaginal surgery.International urogynecology journal · 2020Article
- Revisiting current treatment options for stress urinary incontinence and pelvic organ prolapse: a contemporary literature review.Research and reports in urology · 2019Review
Corrections and comments
- Erratum issued
Authors and funding
9 authors at 1 institution in 1 country.
Funding
Abstract
objectiveTo longitudinally assess the effect of native tissue vaginal apical prolapse repair with anti-incontinence surgery on quality of life, sexual function, and body image between uterosacral and sacrospinous suspensions.
methodsA planned secondary analysis was performed on 374 women enrolled in a randomized trial of the two types of native tissue repair for apical prolapse. Condition-specific and generic quality of life, sexual function, overall and de novo dyspareunia, and body image were assessed using validated instruments at baseline; 6, 12, and 24 months postoperatively; and changes from baseline were assessed and compared between surgical groups. General linear mixed models were used for comparisons and clinically significant differences were assessed using minimum important differences.
resultsOf the women randomized, 82% had outcomes available at 2 years. Overall, clinically and statistically significant improvements in generic and condition-specific quality of life and sexual function were observed after surgery. Dyspareunia rates decreased from 25% to 16% by 24 months with only 3% of all women undergoing treatment. De novo dyspareunia occurred in 5% and 10% by 12 and 24 months, respectively. Body image scores also significantly improved from baseline. There were no clinically meaningful or statistically significant differences between groups for any of these outcomes (all P>.05).
conclusionNative tissue vaginal prolapse surgery results in statistically and clinically significant improvements in quality of life, sexual function, and body image at 24 months with no significant differences between uterosacral and sacrospinous suspensions. One in 10 women experience de novo dyspareunia but few requested treatment. CLINICAL
trial registrationClinicalTrials.gov, www.clinicaltrials.gov, NCT00597935.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.