ArticleAmerican journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics2017
Genome-wide association study of generalized anxiety symptoms in the Hispanic Community Health Study/Study of Latinos.
Article in American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 54 citations in OpenAlex.
- Psychiatric genetics in the diverse landscape of Latin American populations.Nature genetics · 2025Review
- Advancements in genetic research by the Hispanic Community Health Study/Study of Latinos: A 10-year retrospective review.HGG advances · 2025Review
- Comparative Analysis of High-Frequency and Low-Frequency Transcutaneous Electrical Stimulation of the Right Median Nerve in the Regression of Clinical and Neurophysiological Manifestations of Generalized Anxiety Disorder.Journal of clinical medicine · 2024Article
- Involvement of a BH3-only apoptosis sensitizer gene Blm-s in hippocampus-mediated mood control.Translational psychiatry · 2022Article
- Comprehensive and integrative analyses identify TYW5 as a schizophrenia risk gene.BMC medicine · 2022Article
- From genetics to systems biology of stress-related mental disorders.Neurobiology of stress · 2021Article
- Generalized and social anxiety disorder interactomes show distinctive overlaps with striosome and matrix interactomes.Scientific reports · 2021Article
- Social support and strain and emotional distress among Latinos in the northeastern United States.BMC psychology · 2021Article
- Transcriptome-Wide Association Study Provides Insights Into the Genetic Component of Gene Expression in Anxiety.Frontiers in genetics · 2021Article
- A major role for common genetic variation in anxiety disorders.Molecular psychiatry · 2020Article
- Aberrant amplitude low-frequency fluctuation (ALFF) and regional homogeneity (ReHo) in generalized anxiety disorder (GAD) and their roles in predicting treatment remission.Annals of translational medicine · 2020Article
- Heritable natural variation of light/dark preference in an outbred zebrafish population.Journal of neurogenetics · 2019Article
- Genetic Variants Associated With Anxiety and Stress-Related Disorders: A Genome-Wide Association Study and Mouse-Model Study.JAMA psychiatry · 2019Article
- Genetics of Anxiety Disorders.Current psychiatry reports · 2019Review
- Childhood behaviour problems show the greatest gap between DNA-based and twin heritability.Translational psychiatry · 2017Article
- IRF2BP2-deficient microglia block the anxiolytic effect of enhanced postnatal care.Scientific reports · 2017Article
- Genetics of generalized anxiety disorder and related traits.Dialogues in clinical neuroscience · 2017Review
- The Neurobiological Mechanisms of Generalized Anxiety Disorder and Chronic Stress.Chronic stress (Thousand Oaks, Calif.)Article
Corrections and comments
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Authors and funding
18 authors at 12 institutions in 1 country.
Funding
Abstract
Although generalized anxiety disorder (GAD) is heritable and aggregates in families, no genomic loci associated with GAD have been reported. We aimed to discover potential loci by conducting a genome-wide analysis of GAD symptoms in a large, population-based sample of Hispanic/Latino adults. Data came from 12,282 participants (aged 18-74) in the Hispanic Community Health Study/Study of Latinos. Using a shortened Spielberger Trait Anxiety measure, we analyzed the following: (i) a GAD symptoms score restricted to the three items tapping diagnostic features of GAD as defined by DSM-V; and (ii) a total trait anxiety score based on summing responses to all ten items. We first calculated the heritability due to common variants (h
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.