ReviewCureus2016
Proposed Diagnostic Criteria, Classification Schema, and Review of Literature of Notochord-Derived Ecchordosis Physaliphora.
Review in Cureus, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
19 citing papers in PubMed.
- The developing spheno-occipital skull base: developmental variants and embryologic remnants that mimic pathology in children.Pediatric radiology · 2026Review
- Lumbar extradural extraosseous notochordal lesion resulting in radiculopathy: ecchordosis physaliphora versus chordoma. Illustrative case.Journal of neurosurgery. Case lessons · 2026Article
- Cystic Clival Chordoma Presenting With Cerebrospinal Fluid Rhinorrhea: A Case Report and Literature Review.Cureus · 2026Article
- Ecchordosis physaliphora of the clivus: a case series and narrative review of the literature.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2025Review
- Ecchordosis physaliphora presenting as hypnic headache.The neuroradiology journal · 2023Article
- An Ecchordosis Physaliphora, a Rare Entity, Involving the Central Nervous System: A Systematic Review of the Literature.Neurology international · 2023Review
- Chronic cerebrospinal fluid rhinorrhea as an initial presentation of chordoma: illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Spontaneous rhinorrhea: a possible concealing initial symptom of ecchordosis physaliphora. Illustrative case.Journal of neurosurgery. Case lessons · 2023Article
- Endoscopic Endonasal Surgery for Uncommon Pathologies of the Sellar and Parasellar Regions.Advances and technical standards in neurosurgery · 2023Review
- Do All Notochordal Lesions Require Proton Beam Radiotherapy? A Proposed Reclassification of Ecchordosis Physaliphora as Benign Notochord Cell Tumor.Journal of neurological surgery. Part B, Skull base · 2022Article
- Article
- A Cystic Clival Chordoma with CT and MRI Unconventional Appearances.The Indian journal of radiology & imaging · 2022Article
- Indolent multicentric chordoma - A previously undescribed entity: A Case report and literature review.Surgical neurology international · 2022Article
- Pulmonary tumor with Notochordal differentiation: a case report and morphologic, Immunohistochemical and molecular study of benign Notochordal cell tumor originating in the lung.Diagnostic pathology · 2021Article
- Gastrulation : Current Concepts and Implications for Spinal Malformations.Journal of Korean Neurosurgical Society · 2021Article
- Clivus pathologies from diagnosis to surgical multidisciplinary treatment. Review of the literature.Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di otorinolaringologia e chirurgia cervico-facciale · 2021Review
- Article
- State-of-the-Art Imaging in Human Chordoma of the Skull Base.Current radiology reports · 2018Review
- Immunophenotypic features of dedifferentiated skull base chordoma: An insight into the intratumoural heterogeneity.Contemporary oncology (Poznan, Poland) · 2017Review
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ecchordosis physaliphora (EP) is a benign notochordal remnant derived from ectopic nests found along the craniospinal axis. It typically presents asymptomatically and is diagnosed using classic radiologic features, particularly location, T1-hypointensity, T2-hyperintensity, and lack of enhancement following gadolinium (Gd) contrast administration. Distinguishing EP from its malignant counterpart, chordoma, is of paramount importance, given the aggressive nature of the latter. Advances in imaging and immunohistochemistry have aided in diagnosis to an extent but, to our knowledge, identification of the genetic fingerprint of EP has yet to take place. Further cytological analysis of these lesions in search of a genetic link is warranted. We propose here a set of diagnostic criteria based on features consistently cited in the literature. In this literature review, 23 case reports were identified and collated into a summary of symptomatic cases of ecchordosis physaliphora. An illustrative case report of two patients was also included.
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