Evidence map›Paper›PMID 27158521›Full record

ArticleBMJ open diabetes research & care2016

How information about the time requirements and legacy effects of treatments influence decision-making in patients with diabetes and hypertension.

Neda Laiteerapong, Paige C Fairchild, Aviva G Nathan, Michael T Quinn, Elbert S Huang

Abstract read
In one paragraph

Article in BMJ open diabetes research & care, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Neda LaiteerapongSection of General Internal Medicine, Department of Medicine , University of Chicago , Chicago, Illinois , USA.
Paige C FairchildDepartment of Obstetrics and Gynecology , Northwestern University , Chicago, Illinois , USA.
Aviva G NathanSection of General Internal Medicine, Department of Medicine , University of Chicago , Chicago, Illinois , USA.
Michael T QuinnSection of General Internal Medicine, Department of Medicine , University of Chicago , Chicago, Illinois , USA.
Elbert S HuangSection of General Internal Medicine, Department of Medicine , University of Chicago , Chicago, Illinois , USA.

Funding

Northwestern University Clinical and Translational Science Institute (NUCATS)UL1TR001422 · NCATS · NORTHWESTERN UNIVERSITY AT CHICAGO · PI D'AQUILA, RICHARD · 2015 to 2023
$56.8M
Re-Engineering Translational Research at the University of ChicagoUL1TR000430 · NCATS · UNIVERSITY OF CHICAGO · PI SOLWAY, JULIAN · 2012 to 2016
$20.2M
Research Design, Data, and Analytics CoreP30DK092949 · NIDDK · UNIVERSITY OF CHICAGO · PI MONICA E PEEK · 2011 to 2026
$10.0M
Research and Mentorship in Medical Decision Making in DiabetesK24DK105340 · NIDDK · UNIVERSITY OF CHICAGO · PI HUANG, ELBERT S. · 2015 to 2019
$884k
Linking the Legacy Effect in Type 2 Diabetes to Clinical Decision MakingK23DK097283 · NIDDK · UNIVERSITY OF CHICAGO · PI LAITEERAPONG, NEDA · 2012 to 2016
$880k
NCATS NIH HHS UL1 TR000430NCATS NIH HHS UL1 TR001422NIDDK NIH HHS K23 DK097283NIDDK NIH HHS K24 DK105340NIDDK NIH HHS P30 DK092949
6 · The paper itself

Abstract

objectiveWhen deciding about diabetes treatments, patients are typically uninformed about how much time is required before (time requirements), or for how long treatments change outcomes (legacy effects). However, patients may be motivated to adopt treatments with time-related treatment information. We explored whether this information alters a patients' likelihood of starting medications. RESEARCH DESIGN AND

methodsWe conducted semistructured interviews with 60 adults with type 2 diabetes for <10 years and hypertension on oral medications. We measured change in likelihood of starting medications after receiving time requirement (diabetes, 10 years; hypertension, 3 years) and legacy effect (diabetes, 10 additional years; hypertension, none) information. Responses were analyzed for themes about time-related treatment information.

resultsAt baseline, 70% of participants reported being very likely to start a recommended medication. Nearly half (40%) were less likely to start a diabetes medication after being informed of time requirements; but after being informed of legacy effects, 32% reported being more likely. Fewer participants changed likelihoods of starting antihypertensives with time-related information. Many participants expressed that medications' benefits were important to them regardless of time-related information. Participants considered time requirements for diabetes medications too long and compared them to their life expectancy. Many participants were interested in legacy effects of diabetes medications because they looked forward to discontinuing medications, although some expressed doubt that benefits could persist after stopping medications.

conclusionsWhile prolonged time requirements may dissuade patients from adopting treatments, the promise of legacy effects may motivate patients to commit to diabetes treatments.

Indexed as

Decision MakingPatient-Centred CommunicationQualitative Research

Identifiers

PMID27158521
PMCPMC4853808

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.