Evidence map›Paper›PMID 27158452›Full record

ArticleF1000Research2016

A curated compendium of monocyte transcriptome datasets of relevance to human monocyte immunobiology research.

Darawan Rinchai, Sabri Boughorbel, Scott Presnell, Charlie Quinn, Damien Chaussabel

Abstract read
In one paragraph

Article in F1000Research, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Review
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  3. Article
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  7. Article
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  9. Article
  10. Review
  11. Microglial Phenotypes and Functions in Multiple Sclerosis.Cold Spring Harbor perspectives in medicine · 2018
    Review
  12. F1000Research · 2017
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Darawan RinchaiSystems Biology Department, Sidra Medical and Research Center, Doha, Qatar.
Sabri BoughorbelBiomedical Informatics Division, Sidra Medical and Research Center, Doha, Qatar.
Scott PresnellBenaroya Research Institute at Virginia Mason, Seattle, USA.
Charlie QuinnBenaroya Research Institute at Virginia Mason, Seattle, USA.
Damien ChaussabelSystems Biology Department, Sidra Medical and Research Center, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Systems-scale profiling approaches have become widely used in translational research settings. The resulting accumulation of large-scale datasets in public repositories represents a critical opportunity to promote insight and foster knowledge discovery. However, resources that can serve as an interface between biomedical researchers and such vast and heterogeneous dataset collections are needed in order to fulfill this potential. Recently, we have developed an interactive data browsing and visualization web application, the Gene Expression Browser (GXB). This tool can be used to overlay deep molecular phenotyping data with rich contextual information about analytes, samples and studies along with ancillary clinical or immunological profiling data. In this note, we describe a curated compendium of 93 public datasets generated in the context of human monocyte immunological studies, representing a total of 4,516 transcriptome profiles. Datasets were uploaded to an instance of GXB along with study description and sample annotations. Study samples were arranged in different groups. Ranked gene lists were generated based on relevant group comparisons. This resource is publicly available online at http://monocyte.gxbsidra.org/dm3/landing.gsp.

Indexed as

BioinformaticsGene Expression BrowserImmunologyMonocyteTranscriptomics

Identifiers

PMID27158452
PMCPMC4856112

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.