ArticleBiomicrofluidics2016
Investigation of micromixing by acoustically oscillated sharp-edges.
Article in Biomicrofluidics, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
39 citing papers in PubMed.
- 3D printing monolithic, multifunctional polymer acoustofluidic devices with tunable mixing and particle focusing.Lab on a chip · 2026Article
- Research on the Design of Micromixer Based on Acoustic Streaming-Driven Sharp-Edge Structures.Sensors (Basel, Switzerland) · 2025Article
- An Acoustofluidic Device for Sample Preparation and Detection of Small Extracellular Vesicles.Cyborg and bionic systems (Washington, D.C.) · 2025Article
- Acoustohydrodynamic micromixers: Basic mixing principles, programmable mixing prospectives, and biomedical applications.Biomicrofluidics · 2024Review
- Cavity-agnostic acoustofluidic manipulations enabled by guided flexural waves on a membrane acoustic waveguide actuator.Microsystems & nanoengineering · 2024Article
- Pneumatic Microballoons for Active Control of the Vibration-Induced Flow.Micromachines · 2023Article
- Bubble-Based Microrobots with Rapid Circular Motions for Epithelial Pinning and Drug Delivery.Small (Weinheim an der Bergstrasse, Germany) · 2023Article
- Investigating the Performance of the Multi-Lobed Leaf-Shaped Oscillatory Obstacles in Micromixers Using Bulk Acoustic Waves (BAW): Mixing and Chemical Reaction.Micromachines · 2023Article
- A review on microfluidic-assisted nanoparticle synthesis, and their applications using multiscale simulation methods.Discover nano · 2023Review
- Microfluidic Continuous Flow DNA Fragmentation based on a Vibrating Sharp-tip.Microfluidics and nanofluidics · 2022Article
- Bubble-Enhanced Mixing Induced by Standing Surface Acoustic Waves (SSAWs) in Microchannel.Micromachines · 2022Article
- A Numerical Investigation of the Mixing Performance in a Y-Junction Microchannel Induced by Acoustic Streaming.Micromachines · 2022Article
- A simple acoustofluidic device for on-chip fabrication of PLGA nanoparticles.Biomicrofluidics · 2022Article
- One-step enzyme kinetics measurement in 3D printed microfluidics devices based on a high-performance single vibrating sharp-tip mixer.Analytica chimica acta · 2021Article
- Fabrication of tunable, high-molecular-weight polymeric nanoparticlesLab on a chip · 2021Article
- Mixing enhancement in T-junction microchannel with acoustic streaming induced by triangular structure.Biomicrofluidics · 2021Article
- Acoustofluidics-Assisted Fluorescence-SERS Bimodal Biosensors.Small (Weinheim an der Bergstrasse, Germany) · 2020Article
- Acoustic Streaming Generated by Sharp Edges: The Coupled Influences of Liquid Viscosity and Acoustic Frequency.Micromachines · 2020Article
- Acoustofluidics-Assisted Engineering of Multifunctional Three-Dimensional Zinc Oxide Nanoarrays.ACS nano · 2020Article
- A Review of Passive Micromixers with a Comparative Analysis.Micromachines · 2020Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Recently, acoustically oscillated sharp-edges have been utilized to achieve rapid and homogeneous mixing in microchannels. Here, we present a numerical model to investigate acoustic mixing inside a sharp-edge-based micromixer in the presence of a background flow. We extend our previously reported numerical model to include the mixing phenomena by using perturbation analysis and the Generalized Lagrangian Mean (GLM) theory in conjunction with the convection-diffusion equation. We divide the flow variables into zeroth-order, first-order, and second-order variables. This results in three sets of equations representing the background flow, acoustic response, and the time-averaged streaming flow, respectively. These equations are then solved successively to obtain the mean Lagrangian velocity which is combined with the convection-diffusion equation to predict the concentration profile. We validate our numerical model via a comparison of the numerical results with the experimentally obtained values of the mixing index for different flow rates. Further, we employ our model to study the effect of the applied input power and the background flow on the mixing performance of the sharp-edge-based micromixer. We also suggest potential design changes to the previously reported sharp-edge-based micromixer to improve its performance. Finally, we investigate the generation of a tunable concentration gradient by a linear arrangement of the sharp-edge structures inside the microchannel.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.