Evidence map›Paper›PMID 27156368›Full record

ArticleScientific reports2016

The characteristics of circular disposable devices and in situ devices for optimizing male circumcision: a network meta-analysis.

Yu Fan, Dehong Cao, Qiang Wei, Zhuang Tang, Ping Tan, Lu Yang, Liangren Liu, Zhenhua Liu, Xiang Li, Wenbin Xue

Abstract readNetwork Meta-Analysis
In one paragraph

Article in Scientific reports, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Circumcision and its effects in Africa.Translational andrology and urology · 2017
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Yu FanDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Dehong CaoDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Qiang WeiDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Zhuang TangDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Ping TanDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Lu YangDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Liangren LiuDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Zhenhua LiuDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Xiang LiDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.
Wenbin XueDepartment of Urology, Institute of Urology, West China Hospital of Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

In situ device (ISD) and circular disposable device (CDD) are used for optimizing male circumcision (MC), but evidence to explore the characteristics of these two devices is insufficient. In order to explore this issue systematically and provide reliable evidence, ten published randomized controlled trials (RCTs) exploring the safety and efficacy of ISDs and CDDs were included (involving 4649 men). Moderate quality of the RCTs included was found after assessment. Pairwise meta-analyses and network meta-analyses were processed in stata 13.0 and AIDDS v1.16.6 respectively. According to the outcomes that were statistically significant in both pairwise and network meta-analyses, ISD was found to have less intraoperative blood loss (IB), less operative time (OT) and less incidence of wound bleeding (WB) than conventional circumcision (CC); ISD was found to have less WB but more wound healing time (WHT) than CDD; CDD was found to have less IB and less OT than CC. CDD tended to have the best wound healing condition and least pain experience; ISD tended to have the least IB, least OT, least WB, and highest satisfaction rate. With their own superiorities in many aspects, CDD and ISD are both safe and effective devices for optimizing MC.

Indexed as

Circumcision, MaleClinical Trials as TopicHumansMaleOutcome Assessment, Health CarePublication Bias

Identifiers

PMID27156368
PMCPMC4860598

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.