Evidence map›Paper›PMID 27156045›Full record

ArticleJournal of cystic fibrosis : official journal of the European Cystic Fibrosis Society2016

Episodic oral antibiotic use in CF: Discordance between the electronic medical record and self-report.

Lindsay J Caverly, Tanner J Caverly, Linda M Kalikin, Bridget K Foster, Richard H Simon, John J LiPuma

Abstract read
In one paragraph

Article in Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Quantifying variation in home spirometry in people with cystic fibrosis during baseline health, and associations with clinical outcomes.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2024
    Article
  2. Outcomes of cystic fibrosis pulmonary exacerbations treated with antibiotics with activity against anaerobic bacteria.Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society · 2021
    Article
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Lindsay J CaverlyDepartment of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, United States. Electronic address: caverlyl@med.umich.edu.
Tanner J CaverlyDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States; Center for Clinical Management Research, Veterans Affairs, Ann Arbor, MI 48105, United States.
Linda M KalikinDepartment of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Bridget K FosterDepartment of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
Richard H SimonDepartment of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI 48109, United States.
John J LiPumaDepartment of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI 48109, United States.

Funding

Advancing Child Health Through Cellular and Molecular BiologyK12HD028820 · NICHD · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Donna M. Martin · 2002 to 2026
$9.2M
NICHD NIH HHS K12 HD028820
6 · The paper itself

Abstract

backgroundAccurate accounting of antibiotic use is necessary for studies comparing the CF airway microbiota across clinically relevant disease states. While poor adherence to chronic therapies is well described for individuals with CF, use patterns of episodic oral antibiotics are less clear.

methodsEleven individuals with CF completed daily questionnaires regarding antibiotic use for a mean of 458days. Self-report of episodic oral antibiotic use was compared to antibiotic prescription data in the electronic medical record (EMR).

resultsSelf-reported use of episodic oral antibiotics differed from EMR data an average of 8.3% of days per subject. The majority of these discrepancies were due to self-reported use of oral antibiotics outside of the EMR-documented dates of antibiotic prescription.

conclusionsDiscrepancies exist between self-reported use of episodic oral antibiotics and EMR data that have implications for studies of the CF airway microbiota.

Indexed as

Cystic FibrosisSelf MedicationAdministration, OralAdultAnti-Bacterial AgentsDiscriminant AnalysisElectronic Health RecordsFemaleHumansMaleMedication Therapy ManagementMicrobiotaSelf ReportSurveys and QuestionnairesUnited StatesAnti-Bacterial AgentsAdherenceAntibioticsMicrobiome

Identifiers

PMID27156045
PMCPMC5014681

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.