Evidence map›Paper›PMID 27155289›Full record

Trial reportAcademic pediatrics

Effect of Medication Label Units of Measure on Parent Choice of Dosing Tool: A Randomized Experiment.

H Shonna Yin, Ruth M Parker, Lee M Sanders, Benard P Dreyer, Alan Mendelsohn, Stacy Bailey, Deesha A Patel, Jessica J Jimenez, Kwang-Youn A Kim, Kara Jacobson and 6 more

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Academic pediatrics. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
9.0field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 31 citations in OpenAlex.

  1. Trial
  2. Trial
  3. Article
  4. Effect of a Pharmacist-Led Discharge Counseling Service at a Children's Hospital.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG · 2023
    Article
  5. NCPDP recommendations for standardizing dosing in metric units (mL) on prescription container labels of oral liquid medications, version 2.0.American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists · 2021
    Article
  6. Article
  7. Identification of Errors in Pediatric Prescriptions and Interventions to Prevent Errors: A Survey of Community Pharmacists.The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG
    Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

H Shonna YinDepartment of Pediatrics, Bellevue Hospital, New York, NY; Department of Population Health, NYU School of Medicine, New York, NY. Electronic address: yinh02@med.nyu.edu.
Ruth M ParkerDepartment of Medicine, Emory University, Atlanta, Ga.
Lee M SandersDepartment of Pediatrics, Stanford University School of Medicine, Stanford, Calif.
Benard P DreyerDepartment of Pediatrics, Bellevue Hospital, New York, NY.
Alan MendelsohnDepartment of Pediatrics, Bellevue Hospital, New York, NY.
Stacy BaileyDivision of Pharmaceutical Outcomes and Policy, UNC Eshelman School of Pharmacy, Chapel Hill, NC.
Deesha A PatelDivision of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Jessica J JimenezDepartment of Pediatrics, Bellevue Hospital, New York, NY.
Kwang-Youn A KimDepartment of Preventive Medicine, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Kara JacobsonDepartment of Health Policy and Management, Rollins School of Public Health, Emory University, Atlanta, Ga.
Laurie HedlundDivision of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Rosa LandaDepartment of Pediatrics, Stanford University School of Medicine, Stanford, Calif.
Leslie ManessDepartment of Pediatrics, Bellevue Hospital, New York, NY.
Purvi Tailor RaythathaDepartment of Pediatrics, Bellevue Hospital, New York, NY.
Terri McFaddenDepartment of Pediatrics, School of Medicine, Emory University, Atlanta, Ga.
Michael S WolfDivision of General Internal Medicine and Geriatrics, Northwestern University Feinberg School of Medicine, Chicago, Ill.
Bellevue Hospital Center · USNorthwestern University · USEmory University · USStanford University · USUniversity of North Carolina Health Care · US

Funding

Promoting Safe Use of Pediatric Liquid Medications: A Health Literacy ApproachR01HD070864 · NICHD · NEW YORK UNIVERSITY SCHOOL OF MEDICINE · PI YIN, HSIANG · 2012 to 2015
$2.6M
NICHD NIH HHS R01 HD070864
6 · The paper itself

Abstract

objectiveSome experts recommend eliminating "teaspoon" and "tablespoon" terms from pediatric medication dosing instructions, because these terms could inadvertently encourage use of nonstandard tools (ie, kitchen spoons), which are associated with dosing errors. We examined whether use of "teaspoon" or "tsp" on prescription labels affects parents' choice of dosing tools, and the role of health literacy and language.

methodsAnalysis of data collected as part of a controlled experiment (SAFE Rx for Kids [Safe Administration For Every Prescription for Kids] study), which randomized English- and Spanish-speaking parents (n = 2110) of children 8 years of age and younger to 1 of 5 groups, which varied in unit of measurement pairings on medication labels and dosing tools. Outcome assessed was parent self-reported choice of dosing tool. Parent health literacy was measured using the Newest Vital Sign.

resultsSeventy-seven percent had limited health literacy (36.0% low, 41.0% marginal); 35.0% completed assessments in Spanish. Overall, 27.7% who viewed labels containing either "tsp" or "teaspoon" units (alone or with "mL") chose nonstandard dosing tools (ie, kitchen teaspoon, kitchen tablespoon), compared with 8.3% who viewed "mL"-only labels (adjusted odds ratio [AOR] = 4.4 [95% confidence interval (CI), 3.3-5.8]). Odds varied based on whether "teaspoon" was spelled out or abbreviated ("teaspoon"-alone: AOR = 5.3 [95% CI, 3.8-7.3]); "teaspoon" with mL: AOR = 4.7 [95% CI, 3.3-6.5]; "tsp" with mL: AOR = 3.3 [95% CI, 2.4-4.7]; P < .001). Similar findings were noted across health literacy and language groups.

conclusionsUse of teaspoon units ("teaspoon" or "tsp") on prescription labels is associated with increased likelihood of parent choice of nonstandard dosing tools. Future studies might be helpful to examine the real-world effect of eliminating teaspoon units from medication labels, and identify additional strategies to promote the safe use of pediatric liquid medications.

Indexed as

Choice BehaviorDrug LabelingHealth LiteracyLanguageParentsAdultBlack or African AmericanChildChild, PreschoolFemaleHispanic or LatinoHumansInfantInfant, NewbornMaleMedication ErrorsPharmaceutical Preparationsambulatory caredosing errorshealth communicationhealth literacyinjury preventionmedication errors

Identifiers

PMID27155289
PMCPMC5077678
OpenAlexW2345330307

What OpenQuestion holds

Textmetadata
LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.