ArticlePlant biotechnology journal2016
Domestication and the storage starch biosynthesis pathway: signatures of selection from a whole sorghum genome sequencing strategy.
Article in Plant biotechnology journal, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed, 51 citations in OpenAlex.
- Effects of a novel loss-of-function waxy endosperm allele on sorghum seed development and grain quality.G3 (Bethesda, Md.) · 2025Article
- Transcriptome-wide expression landscape and starch synthesis pathway co-expression network in sorghum.The plant genome · 2024Article
- Genome-Wide Identification of DOF Gene Family and the Mechanism Dissection ofInternational journal of molecular sciences · 2022Article
- Profiling of transcriptional regulators associated with starch biosynthesis in sorghum (Frontiers in plant science · 2022Article
- Genetic diversity, population structure, and selection signature in Ethiopian sorghum [Sorghum bicolor L. (Moench)] germplasm.G3 (Bethesda, Md.) · 2021Article
- Genetic diversity for starch quality and alkali spreading value in sorghum.The plant genome · 2021Article
- The Road to Sorghum Domestication: Evidence From Nucleotide Diversity and Gene Expression Patterns.Frontiers in plant science · 2021Article
- Applications of Multi-Omics Technologies for Crop Improvement.Frontiers in plant science · 2021Review
- Genome wide association mapping of epi-cuticular wax genes inPhysiology and molecular biology of plants : an international journal of functional plant biology · 2020Article
- Genetic Diversity of CGenes · 2020Article
- The improved assembly of 7DL chromosome provides insight into the structure and evolution of bread wheat.Plant biotechnology journal · 2020Article
- Mutations in sorghum SBEIIb and SSIIa affect alkali spreading value, starch composition, thermal properties and flour viscosity.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2019Article
- Transcriptome and metabolome reveal distinct carbon allocation patterns during internode sugar accumulation in different sorghum genotypes.Plant biotechnology journal · 2019Article
- Common metabolic networks contribute to carbon sink strength of sorghum internodes: implications for bioenergy improvement.Biotechnology for biofuels · 2019Article
- Molecular basis of African yam domestication: analyses of selection point to root development, starch biosynthesis, and photosynthesis related genes.BMC genomics · 2017Article
- Genetic dissection of sorghum grain quality traits using diverse and segregating populations.TAG. Theoretical and applied genetics. Theoretische und angewandte Genetik · 2017Article
- Whole-Genome Analysis of Candidate genes Associated with Seed Size and Weight inFrontiers in plant science · 2017Article
- Whole Genome Sequencing Reveals Potential New Targets for Improving Nitrogen Uptake and Utilization inFrontiers in plant science · 2016Article
Corrections and comments
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Authors and funding
9 authors at 4 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Next-generation sequencing of complete genomes has given researchers unprecedented levels of information to study the multifaceted evolutionary changes that have shaped elite plant germplasm. In conjunction with population genetic analytical techniques and detailed online databases, we can more accurately capture the effects of domestication on entire biological pathways of agronomic importance. In this study, we explore the genetic diversity and signatures of selection in all predicted gene models of the storage starch synthesis pathway of Sorghum bicolor, utilizing a diversity panel containing lines categorized as either 'Landraces' or 'Wild and Weedy' genotypes. Amongst a total of 114 genes involved in starch synthesis, 71 had at least a single signal of purifying selection and 62 a signal of balancing selection and others a mix of both. This included key genes such as STARCH PHOSPHORYLASE 2 (SbPHO2, under balancing selection), PULLULANASE (SbPUL, under balancing selection) and ADP-glucose pyrophosphorylases (SHRUNKEN2, SbSH2 under purifying selection). Effectively, many genes within the primary starch synthesis pathway had a clear reduction in nucleotide diversity between the Landraces and wild and weedy lines indicating that the ancestral effects of domestication are still clearly identifiable. There was evidence of the positional rate variation within the well-characterized primary starch synthesis pathway of sorghum, particularly in the Landraces, whereby low evolutionary rates upstream and high rates downstream in the metabolic pathway were expected. This observation did not extend to the wild and weedy lines or the minor starch synthesis pathways.
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