Evidence map›Paper›PMID 27155044›Full record

ArticleJournal of theoretical biology2017

Modeling calcium waves in an anatomically accurate three-dimensional parotid acinar cell.

James Sneyd, Shawn Means, Di Zhu, John Rugis, Jong Hak Won, David I Yule

Open access · greenAbstract read
In one paragraph

Article in Journal of theoretical biology, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.5field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Intracellular CaiScience · 2024
    Article
  2. Computer-Assisted Proofs of Hopf Bubbles and Degenerate Hopf Bifurcations.Journal of dynamics and differential equations · 2024
    Article
  3. Computational investigation of IPScientific reports · 2023
    Article
  4. Article
  5. IPeLife · 2020
    Article
  6. CaCold Spring Harbor perspectives in biology · 2020
    Review
  7. A Model ofBulletin of mathematical biology · 2019
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

James SneydDepartment of Mathematics, University of Auckland, New Zealand. Electronic address: j.sneyd@auckland.ac.nz.
Shawn MeansDepartment of Mathematics, University of Auckland, New Zealand.
Di ZhuDepartment of Mathematics, University of Auckland, New Zealand.
John RugisDepartment of Mathematics, University of Auckland, New Zealand.
Jong Hak WonDepartment of Pharmacology and Physiology, University of Rochester Medical Centre, Rochester, USA.
David I YuleDepartment of Pharmacology and Physiology, University of Rochester Medical Centre, Rochester, USA.
University of Auckland · NZUniversity of Rochester Medical Center · US

Funding

An experimental/computational approach for understanding salivary fluid secretionR01DE019245 · NIDCR · UNIVERSITY OF ROCHESTER · PI David I Yule · 2008 to 2026
$9.7M
NIDCR NIH HHS R01 DE019245
6 · The paper itself

Abstract

We construct a model of calcium waves in a three-dimensional anatomically accurate parotid acinar cell, constructed from experimental data. Gradients of inositol trisphosphate receptor (IPR) density are imposed, with the IPR density being greater closer to the lumen, which has a branched structure, and inositol trisphosphate (IP

Indexed as

AlgorithmsCalcium SignalingModels, BiologicalAcinar CellsAnimalsCalciumComputer SimulationHumansInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsIon TransportParotid GlandRyanodine Receptor Calcium Release ChannelSalivaCalciumInositol 1,4,5-TrisphosphateInositol 1,4,5-Trisphosphate ReceptorsRyanodine Receptor Calcium Release ChannelCalcium oscillationsInositol trisphosphate receptorMultiscale modelingRyanodine receptorSaliva secretion

Identifiers

PMID27155044
PMCPMC5444919
OpenAlexW2346709345

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.