ArticleHPB : the official journal of the International Hepato Pancreato Biliary Association2016
The many faces of ALPPS: surgical indications and techniques among surgeons collaborating in the international registry.
Article in HPB : the official journal of the International Hepato Pancreato Biliary Association, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- [Conditioning and systemic treatment before extensive liver resection].Chirurgie (Heidelberg, Germany) · 2026Review
- Therapeutic priming of liver regeneration: from mechanisms toFrontiers in transplantation · 2026Review
- Augmenting the Future Liver Remnant Prior to Major Hepatectomy: A Review of Options on the Menu.Annals of surgical oncology · 2025Review
- Role of liver augmentation prior to hepatic resection - a survey on standards, procedures, and indications in Germany, Switzerland, and Austria.Langenbeck's archives of surgery · 2024Article
- A novel comprehensive ALPPS preoperative risk assessment (CAPRA) score is beneficial in creating a treatment strategy for advanced liver malignancy.Hepatobiliary surgery and nutrition · 2023Article
- Imaging-guided interventions modulating portal venous flow: Evidence and controversies.JHEP reports : innovation in hepatology · 2022Review
- The impact of associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) on liver tumors with unusual indications.Hepatobiliary surgery and nutrition · 2022Article
- Chinese expert consensus on conversion therapy for hepatocellular carcinoma (2021 edition).Hepatobiliary surgery and nutrition · 2022Review
- Comment on Liver Venous Deprivation or Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy?: A Retrospective Multicentric Study.Annals of surgery open : perspectives of surgical history, education, and clinical approaches · 2022Article
- Current trends in regenerative liver surgery: Novel clinical strategies and experimental approaches.Frontiers in surgery · 2022Review
- Associating liver partition and portal vein ligation for staged hepatectomy (ALPPS) in colorectal liver metastases: review of the literature.Clinical and experimental hepatology · 2021Review
- Colorectal liver metastases: Current management and future perspectives.World journal of clinical oncology · 2020Review
- Liver venous deprivation versus portal vein embolization before major hepatectomy: future liver remnant volumetric and functional changes.Hepatobiliary surgery and nutrition · 2020Article
- Associated liver partition and portal vein ligation for staged hepatectomy: a review.Translational gastroenterology and hepatology · 2020Review
- Current status of associating liver partition with portal vein ligation for staged hepatectomy: Comparison with two-stage hepatectomy and strategies for better outcomes.World journal of gastroenterology · 2019Review
- Did the International ALPPS Meeting 2015 Have an Impact on Daily Practice? The Hamburg Barmbek Experience of 58 Cases.Visceral medicine · 2017Article
- Extended liver venous deprivation before major hepatectomy induces marked and very rapid increase in future liver remnant function.European radiology · 2017Article
- The rush to novelty and high expectations in surgery: the case of ALPPS.Journal of clinical and translational research · 2016Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundALPPS was developed to induce accelerated future liver remnant (FLR) hypertrophy in order to increase hepatic tumour resectability and reduce the risk of post-operative liver failure. While early studies demonstrated concerning complication rates, others reported favourable results. This inconsistency may be due to variability in surgical indications and technique.
methodsA web-based survey was sent to surgeons participating in the International ALPPS Registry in September of 2014. Questions addressed surgeon demographics and training, surgical indications and technique, and clinical management approaches.
resultsFifty six out of 85 surgeons from 78 centers responded (66%) and half (n = 30) had training in liver transplantation. Forty seven (84%) did not reserve ALPPS solely for colorectal liver metastases (CRLM) and 30 (54%) would perform ALPPS for an FLR over 30%. Neoadjuvant chemotherapy for CRLM was recommended by 37 (66%) respondents. Surgical approaches varied considerably, with 30% not preserving outflow to the middle hepatic vein and 39% believing it necessary to skeletonize the hepatoduodenal ligament. Twenty five (45%) surgeons have observed segment 4 necrosis.
conclusionThere is considerable variability in how ALPPS is performed internationally. This heterogeneity in practice patterns may explain the current incongruity in published outcomes, and highlights the need for standardization.
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