Evidence map›Paper›PMID 27154744›Full record

ReviewClinical science (London, England : 1979)2016

GPER-novel membrane oestrogen receptor.

Margaret A Zimmerman, Rebecca A Budish, Shreya Kashyap, Sarah H Lindsey

Open access · greenAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Clinical science (London, England : 1979), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.

0numbers the graph read from it
0cells of the map it votes in
62citing papers in PubMed
9.6field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

62 citing papers in PubMed, 113 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Chapter 3. Impact of estrogens on hemostasis.Frontiers in endocrinology · 2025
    Review
  6. Article
  7. Review
  8. Review
  9. Review
  10. Review
  11. Article
  12. Review
  13. Review
  14. Review
  15. Article
  16. Minireview: Parabens Exposure and Breast Cancer.International journal of environmental research and public health · 2022
    Review
  17. Review
  18. Review
  19. Article
  20. Article

2 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Margaret A ZimmermanDepartment of Pharmacology, Tulane University, New Orleans, LA, U.S.A.
Rebecca A BudishDepartment of Pharmacology, Tulane University, New Orleans, LA, U.S.A.
Shreya KashyapDepartment of Pharmacology, Tulane University, New Orleans, LA, U.S.A.
Sarah H LindseyDepartment of Pharmacology, Tulane University, New Orleans, LA, U.S.A. lindsey@tulane.edu.
Tulane University · US

Funding

Vascular Interactions of Estrogen Receptor GPR30 and the Renin-Angiotensin SystemR00HL103974 · NHLBI · TULANE UNIVERSITY OF LOUISIANA · PI LINDSEY, SARAH H. · 2012 to 2014
$710k
Vascular Interactions of Estrogen Receptor GPR30 and the Renin-Angiotensin SystemK99HL103974 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI LINDSEY, SARAH H. · 2011 to 2011
$97k
NHLBI NIH HHS K99 HL103974NHLBI NIH HHS R00 HL103974
6 · The paper itself

Abstract

The recent discovery of the G protein-coupled oestrogen receptor (GPER) presents new challenges and opportunities for understanding the physiology, pathophysiology and pharmacology of many diseases. This review will focus on the expression and function of GPER in hypertension, kidney disease, atherosclerosis, vascular remodelling, heart failure, reproduction, metabolic disorders, cancer, environmental health and menopause. Furthermore, this review will highlight the potential of GPER as a therapeutic target.

Indexed as

AnimalsEstrogensHumansHypertensionKidney DiseasesReceptors, EstrogenReceptors, G-Protein-CoupledEstrogensGPER1 protein, humanReceptors, EstrogenReceptors, G-Protein-CoupledcancercardiovascularGPR30menopausemetabolismreproduction

Identifiers

PMID27154744
PMCPMC5125080
OpenAlexW2346690690

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.