Evidence map›Paper›PMID 27154185›Full record

ArticleSexually transmitted infections2017

Serosorting and recreational drug use are risk factors for diagnosis of genital infection with chlamydia and gonorrhoea among HIV-positive men who have sex with men: results from a clinical cohort in Ontario, Canada.

Ramandip Grewal, Vanessa G Allen, Sandra Gardner, Veronika Moravan, Darrell H S Tan, Janet Raboud, Ahmed M Bayoumi, Rupert Kaul, Tony Mazzulli, Frank McGee and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Sexually transmitted infections, 2017. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
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  7. Canadian results from the European Men-who-have-sex-with-men Internet survey (EMIS-2017).Canada communicable disease report = Releve des maladies transmissibles au Canada · 2019
    Article
  8. Article
  9. Article
  10. Risk Factors and Incidence of Syphilis in Human Immunodeficiency Virus (HIV)-Infected Persons: The HIV Outpatient Study, 1999-2015.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2018
    Observational
  11. Article
  12. Article
  13. Article
  14. Syphilis and HIV: Is HAART at the heart of this epidemic?Sexually transmitted infections · 2017
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 7 institutions in 1 country.

Ramandip GrewalCentre for Research on Inner City Health, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Vanessa G AllenPublic Health Laboratories, Public Health Ontario, Toronto, Ontario, Canada.
Sandra GardnerDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Veronika MoravanOntario HIV Treatment Network, Toronto, Ontario, Canada.
Darrell H S TanDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.ORCID http://orcid.org/0000-0002-3069-2875
Janet RaboudDalla Lana School of Public Health, University of Toronto, Toronto, Ontario, Canada.
Ahmed M BayoumiCentre for Research on Inner City Health, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Rupert KaulDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Tony MazzulliPublic Health Laboratories, Public Health Ontario, Toronto, Ontario, Canada.
Frank McGeeAIDS Bureau, Ontario Ministry of Health and Long-Term Care, Toronto, Ontario, Canada.
Sean B RourkeCentre for Research on Inner City Health, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
Ann N BurchellCentre for Research on Inner City Health, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, Ontario, Canada.
OHTN Cohort Study Research Team
St. Michael's Hospital · CAUniversity of Toronto · CAMinistry of Health and Long Term Care · CAMount Sinai Hospital · CAOntario HIV Treatment Network · CAToronto Public Health · CAUniversity Health Network · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesRates of chlamydia and gonorrhoea have been rising in urban centres in Canada, particularly among HIV-positive men who have sex with men (MSM). Our objective was to identify behavioural risk factors for diagnosis with chlamydia and gonorrhoea in this population, with a focus on the HIV status of sexual partners.

methodsThe OHTN Cohort Study follows people in HIV care across Ontario. We restricted the analysis to 1997 MSM who completed questionnaires in 2010-2013 at one of seven clinics that submit all chlamydia and gonorrhoea tests to the provincial public health laboratory; we obtained test results via record linkage. We estimated cumulative incidences using Kaplan-Meier methods and identified risk factors for diagnosis of a composite outcome (chlamydia or gonorrhoea infection) using Cox regression.

resultsAt follow-up, there were 74 new chlamydia/gonorrhoea diagnoses with a 12-month cumulative incidence of 1.7% (95% CI 1.1% to 2.2%). Risk factors for chlamydia/gonorrhoea diagnosis were: 5+ HIV-positive partners (HR=3.3, 95% CI 1.4 to 7.8; reference=none) and recreational drug use (HR=2.2, 95% CI 1.2 to 3.9).

conclusionsHeightened risks with recreational drug use and multiple HIV-positive partners suggest that chlamydia/gonorrhoea may have achieved high prevalence in certain sexual networks among HIV-positive MSM. Interventions to promote safer sex and timely testing among MSM are needed.

Indexed as

Illicit DrugsChlamydia InfectionsGonorrheaHIV InfectionsHIV SerosortingHomosexuality, MaleHumansMaleOntarioPrevalenceRisk FactorsSubstance-Related DisordersIllicit DrugsCHLAMYDIA INFECTIONGAY MENGONORRHOEAHIVSEXUAL BEHAVIOUR

Identifiers

PMID27154185
PMCPMC5293859
OpenAlexW2347113562

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.