ArticleJournal of the American Society of Nephrology : JASN2016
Neither Hematocrit Normalization nor Exercise Training Restores Oxygen Consumption to Normal Levels in Hemodialysis Patients.
Article in Journal of the American Society of Nephrology : JASN, 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 2 of them syntheses that pooled it.
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The trial behind it
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Who cites it
23 citing papers in PubMed, 2 syntheses or guidelines pooled it, 32 citations in OpenAlex.
- Exercise training for adults undergoing maintenance dialysis.The Cochrane database of systematic reviews · 2022Pooled it
- Pooled it
- A randomized trial of aerobic exercise in chronic kidney disease: Evidence for blunted cardiopulmonary adaptations.Annals of physical and rehabilitation medicine · 2021Trial
- The effect of dietary nitrate on exercise capacity in chronic kidney disease: a randomized controlled pilot study.Nitric oxide : biology and chemistry · 2021Trial
- Peak oxygen consumption is positively associated with estimates of oxygen extraction and microvascular blood volume in veterans with chronic kidney disease.American journal of physiology. Renal physiology · 2026Article
- Exercise training for adults with chronic kidney disease not requiring dialysis.The Cochrane database of systematic reviews · 2026Article
- Article
- Exercise limitation in chronic kidney disease: An experimental pilot study with leg and arm exercise.Physiological reports · 2025Article
- Review of Exercise Interventions to Improve Clinical Outcomes in Nondialysis CKD.Kidney international reports · 2024Review
- Cardiac dysfunction in dialysing adults with end-stage kidney disease is associated with exercise intolerance: A pilot observational study.Physiological reports · 2024Observational
- Exercise for patients with chronic kidney disease: from cells to systems to function.American journal of physiology. Renal physiology · 2024Review
- Physical Activity and Exercise for Cardiorespiratory Health and Fitness in Chronic Kidney Disease.Reviews in cardiovascular medicine · 2022Article
- Endothelial glycocalyx is damaged in diabetic cardiomyopathy: angiopoietin 1 restores glycocalyx and improves diastolic function in mice.Diabetologia · 2022Article
- A clinical evaluation of VOEuropean journal of applied physiology · 2021Article
- Exercise intolerance in kidney diseases: physiological contributors and therapeutic strategies.American journal of physiology. Renal physiology · 2021Review
- Impact of Low Hemoglobin on Body Composition, Strength, and Redox Status of Older Hemodialysis Patients Following Resistance Training.Frontiers in physiology · 2021Article
- Microvascular disease in chronic kidney disease: the base of the iceberg in cardiovascular comorbidity.Clinical science (London, England : 1979) · 2020Review
- Time to rehabilitate the idea of exercise for patients with chronic kidney disease?Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2019Article
- Cardiopulmonary exercise testing reveals subclinical abnormalities in chronic kidney disease.European journal of preventive cardiology · 2018Article
- Gradual reduction in exercise capacity in chronic kidney disease is associated with systemic oxygen delivery factors.PloS one · 2018Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Patients treated with hemodialysis develop severely reduced functional capacity, which can be partially ameliorated by correcting anemia and through exercise training. In this study, we determined perturbations of an erythroid-stimulating agent and exercise training to examine if and where limitation to oxygen transport exists in patients on hemodialysis. Twenty-seven patients on hemodialysis completed a crossover study consisting of two exercise training phases at two hematocrit (Hct) values: 30% (anemic) and 42% (physiologic; normalized by treatment with erythroid-stimulating agent). To determine primary outcome measures of peak power and oxygen consumption (VO
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