ArticleCritical care (London, England)2016
Presentation and outcome of Middle East respiratory syndrome in Saudi intensive care unit patients.
Article in Critical care (London, England), 2016. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 7 of them syntheses that pooled it.
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Who cites it
43 citing papers in PubMed, 7 syntheses or guidelines pooled it.
- Comparison of confirmed COVID-19 with SARS and MERS cases - Clinical characteristics, laboratory findings, radiographic signs and outcomes: A systematic review and meta-analysis.Reviews in medical virology · 2020Pooled it
- Pharmacologic Treatments and Supportive Care for Middle East Respiratory Syndrome.Emerging infectious diseases · 2020Pooled it
- Rate of Intensive Care Unit admission and outcomes among patients with coronavirus: A systematic review and Meta-analysis.PloS one · 2020Pooled it
- MERS transmission and risk factors: a systematic review.BMC public health · 2018Pooled it
- Clinical determinants of the severity of Middle East respiratory syndrome (MERS): a systematic review and meta-analysis.BMC public health · 2016Pooled it
- Asymptomatic Middle East Respiratory Syndrome Coronavirus (MERS-CoV) infection: Extent and implications for infection control: A systematic review.Travel medicine and infectious diseasePooled it
- A Systematic Review of therapeutic agents for the treatment of the Middle East Respiratory Syndrome Coronavirus (MERS-CoV).Travel medicine and infectious diseasePooled it
- The Effectiveness of a Four-Week Digital Physiotherapy Intervention to Improve Functional Capacity and Adherence to Intervention in Patients with Long COVID-19.International journal of environmental research and public health · 2022Trial
- Extracorporeal membrane oxygenation support for tropical infections: a scoping review.Journal of intensive care · 2026Review
- Prognostic value of oxygen saturation index trajectory phenotypes on ICU mortality in mechanically ventilated patients: a multi-database retrospective cohort study.Journal of intensive care · 2023Article
- Increased complications of COVID-19 in people with cardiovascular disease: Role of the renin-angiotensin-aldosterone system (RAAS) dysregulation.Chemico-biological interactions · 2022Review
- Controversies' clarification regarding ribavirin efficacy in measles and coronaviruses: Comprehensive therapeutic approach strictly tailored to COVID-19 disease stages.World journal of clinical cases · 2021Article
- Global prevalence and determinants of mortality among patients with COVID-19: A systematic review and meta-analysis.Annals of medicine and surgery (2012) · 2021Review
- Telerehabilitation Intervention in Patients with COVID-19 after Hospital Discharge to Improve Functional Capacity and Quality of Life. Study Protocol for a Multicenter Randomized Clinical Trial.International journal of environmental research and public health · 2021Article
- Outcome of Middle East Respiratory Syndrome (MERS) in hematology and oncology patients: A case series in Saudi Arabia.Journal of infection and public health · 2021Article
- Convalescent plasma therapy for coronavirus infection: experience from MERS and application in COVID-19.Human vaccines & immunotherapeutics · 2020Review
- Epidemic and pandemic viral infections: impact on tuberculosis and the lung: A consensus by the World Association for Infectious Diseases and Immunological Disorders (WAidid), Global Tuberculosis Network (GTN), and members of the European Society of Clinical Microbiology and Infectious Diseases Study Group for Mycobacterial Infections (ESGMYC).The European respiratory journal · 2020Review
- Early Stage Machine Learning-Based Prediction of US County Vulnerability to the COVID-19 Pandemic: Machine Learning Approach.JMIR public health and surveillance · 2020Article
- Obese communities among the best predictors of COVID-19-related deaths.Cardiovascular endocrinology & metabolism · 2020Article
- A comparative overview of COVID-19, MERS and SARS: Review article.International journal of surgery (London, England) · 2020Review
Corrections and comments
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Authors and funding
14 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMiddle East respiratory syndrome coronavirus infection is associated with high mortality rates but limited clinical data have been reported. We describe the clinical features and outcomes of patients admitted to an intensive care unit (ICU) with Middle East respiratory syndrome coronavirus (MERS-CoV) infection.
methodsRetrospective analysis of data from all adult (>18 years old) patients admitted to our 20-bed mixed ICU with Middle East respiratory syndrome coronavirus infection between October 1, 2012 and May 31, 2014. Diagnosis was confirmed in all patients using real-time reverse transcription polymerase chain reaction on respiratory samples.
resultsDuring the observation period, 31 patients were admitted with MERS-CoV infection (mean age 59 ± 20 years, 22 [71 %] males). Cough and tachypnea were reported in all patients; 22 (77.4 %) patients had bilateral pulmonary infiltrates. Invasive mechanical ventilation was applied in 27 (87.1 %) and vasopressor therapy in 25 (80.6 %) patients during the intensive care unit stay. Twenty-three (74.2 %) patients died in the ICU. Nonsurvivors were older, had greater APACHE II and SOFA scores on admission, and were more likely to have received invasive mechanical ventilation and vasopressor therapy. After adjustment for the severity of illness and the degree of organ dysfunction, the need for vasopressors was an independent risk factor for death in the ICU (odds ratio = 18.33, 95 % confidence interval: 1.11-302.1, P = 0.04).
conclusionsMERS-CoV infection requiring admission to the ICU is associated with high morbidity and mortality. The need for vasopressor therapy is the main risk factor for death in these patients.
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